Fluid shear stress activates YAP1 to promote cancer cell motility

Fluid frictional forces around cancer cells influence chemokine production and delivery of chemotherapeutic drugs but it is unclear if they directly impact tumour biology through biomechanical effects. Here, the authors show that wall shear stress stimulates cancer cell migration through a ROCK–LIMK...

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Autores principales: Hyun Jung Lee, Miguel F. Diaz, Katherine M. Price, Joyce A. Ozuna, Songlin Zhang, Eva M. Sevick-Muraca, John P. Hagan, Pamela L. Wenzel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/8e8007f0521c4fb5861ef0ff47661f28
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