Crystallization after intravitreal ganciclovir injection

Pitipol Choopong, Nattaporn Tesavibul, Nattawut RodanantDepartment of Ophthalmology, Siriraj Hospital, Mahidol University, Bangkok, ThailandPurpose: To report crystal formation as a complication of intravitreal ganciclovir injection.Patients and methods: A 73-year-old female patient with unilateral...

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Autores principales:	Pitipol Choopong, Nattaporn Tesavibul, Nattawut Rodanant
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/8e813464a6b14a87a3173e1a9b475e8f
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spelling	oai:doaj.org-article:8e813464a6b14a87a3173e1a9b475e8f2021-12-02T07:31:38ZCrystallization after intravitreal ganciclovir injection1177-54671177-5483https://doaj.org/article/8e813464a6b14a87a3173e1a9b475e8f2010-07-01T00:00:00Zhttp://www.dovepress.com/crystallization-after-intravitreal-ganciclovir-injection-a4847https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Pitipol Choopong, Nattaporn Tesavibul, Nattawut RodanantDepartment of Ophthalmology, Siriraj Hospital, Mahidol University, Bangkok, ThailandPurpose: To report crystal formation as a complication of intravitreal ganciclovir injection.Patients and methods: A 73-year-old female patient with unilateral cytomegalovirus retinitis was treated with intravitreous ganciclovir (4 mg/0.04 mL).Results: After the intravitreal injection, sudden crystallization was observed in the vitreous. The patient experienced marked reduction in visual acuity and increased intraocular pressure. Despite aqueous paracenthesis and pars plana vitrectomy, optic atrophy was observed and her visual acuity remained unimproved after 12 months.Conclusion: Crystal formation can occur as a complication of intravitreal ganciclovir injection. Associated retinal and optic nerve damage was found which results in permanent visual morbidity.Keywords: ganciclovir, intravitreal injection, intraocular, CMV, toxicity Pitipol ChoopongNattaporn TesavibulNattawut RodanantDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 709-711 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Pitipol Choopong Nattaporn Tesavibul Nattawut Rodanant Crystallization after intravitreal ganciclovir injection
description	Pitipol Choopong, Nattaporn Tesavibul, Nattawut RodanantDepartment of Ophthalmology, Siriraj Hospital, Mahidol University, Bangkok, ThailandPurpose: To report crystal formation as a complication of intravitreal ganciclovir injection.Patients and methods: A 73-year-old female patient with unilateral cytomegalovirus retinitis was treated with intravitreous ganciclovir (4 mg/0.04 mL).Results: After the intravitreal injection, sudden crystallization was observed in the vitreous. The patient experienced marked reduction in visual acuity and increased intraocular pressure. Despite aqueous paracenthesis and pars plana vitrectomy, optic atrophy was observed and her visual acuity remained unimproved after 12 months.Conclusion: Crystal formation can occur as a complication of intravitreal ganciclovir injection. Associated retinal and optic nerve damage was found which results in permanent visual morbidity.Keywords: ganciclovir, intravitreal injection, intraocular, CMV, toxicity
format	article
author	Pitipol Choopong Nattaporn Tesavibul Nattawut Rodanant
author_facet	Pitipol Choopong Nattaporn Tesavibul Nattawut Rodanant
author_sort	Pitipol Choopong
title	Crystallization after intravitreal ganciclovir injection
title_short	Crystallization after intravitreal ganciclovir injection
title_full	Crystallization after intravitreal ganciclovir injection
title_fullStr	Crystallization after intravitreal ganciclovir injection
title_full_unstemmed	Crystallization after intravitreal ganciclovir injection
title_sort	crystallization after intravitreal ganciclovir injection
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/8e813464a6b14a87a3173e1a9b475e8f
work_keys_str_mv	AT pitipolchoopong crystallizationafterintravitrealganciclovirinjection AT nattaporntesavibul crystallizationafterintravitrealganciclovirinjection AT nattawutrodanant crystallizationafterintravitrealganciclovirinjection
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Crystallization after intravitreal ganciclovir injection

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