The Acinetobacter baumannii disinfectant resistance protein, AmvA, is a spermidine and spermine efflux pump

Francesca Short et al. identify natural polyamines as substrates for a drug efflux pump in the clinically-relevant pathogen, Acinetobacter baumannii. Their results suggest that efflux pumps now known to be involved in drug resistance may have originated as polyamine transporters.

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Autores principales:	Francesca L. Short, Qi Liu, Bhumika Shah, Heather E. Clift, Varsha Naidu, Liping Li, Farzana T. Prity, Bridget C. Mabbutt, Karl A. Hassan, Ian T. Paulsen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/8e858361117f461b89e8f68cd27b2273
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spelling	oai:doaj.org-article:8e858361117f461b89e8f68cd27b22732021-12-02T17:26:48ZThe Acinetobacter baumannii disinfectant resistance protein, AmvA, is a spermidine and spermine efflux pump10.1038/s42003-021-02629-62399-3642https://doaj.org/article/8e858361117f461b89e8f68cd27b22732021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02629-6https://doaj.org/toc/2399-3642Francesca Short et al. identify natural polyamines as substrates for a drug efflux pump in the clinically-relevant pathogen, Acinetobacter baumannii. Their results suggest that efflux pumps now known to be involved in drug resistance may have originated as polyamine transporters.Francesca L. ShortQi LiuBhumika ShahHeather E. CliftVarsha NaiduLiping LiFarzana T. PrityBridget C. MabbuttKarl A. HassanIan T. PaulsenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Francesca L. Short Qi Liu Bhumika Shah Heather E. Clift Varsha Naidu Liping Li Farzana T. Prity Bridget C. Mabbutt Karl A. Hassan Ian T. Paulsen The Acinetobacter baumannii disinfectant resistance protein, AmvA, is a spermidine and spermine efflux pump
description	Francesca Short et al. identify natural polyamines as substrates for a drug efflux pump in the clinically-relevant pathogen, Acinetobacter baumannii. Their results suggest that efflux pumps now known to be involved in drug resistance may have originated as polyamine transporters.
format	article
author	Francesca L. Short Qi Liu Bhumika Shah Heather E. Clift Varsha Naidu Liping Li Farzana T. Prity Bridget C. Mabbutt Karl A. Hassan Ian T. Paulsen
author_facet	Francesca L. Short Qi Liu Bhumika Shah Heather E. Clift Varsha Naidu Liping Li Farzana T. Prity Bridget C. Mabbutt Karl A. Hassan Ian T. Paulsen
author_sort	Francesca L. Short
title	The Acinetobacter baumannii disinfectant resistance protein, AmvA, is a spermidine and spermine efflux pump
title_short	The Acinetobacter baumannii disinfectant resistance protein, AmvA, is a spermidine and spermine efflux pump
title_full	The Acinetobacter baumannii disinfectant resistance protein, AmvA, is a spermidine and spermine efflux pump
title_fullStr	The Acinetobacter baumannii disinfectant resistance protein, AmvA, is a spermidine and spermine efflux pump
title_full_unstemmed	The Acinetobacter baumannii disinfectant resistance protein, AmvA, is a spermidine and spermine efflux pump
title_sort	acinetobacter baumannii disinfectant resistance protein, amva, is a spermidine and spermine efflux pump
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8e858361117f461b89e8f68cd27b2273
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The Acinetobacter baumannii disinfectant resistance protein, AmvA, is a spermidine and spermine efflux pump

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