Working memory accuracy for multiple targets is driven by reward expectation and stimulus contrast with different time-courses

Abstract The richness of sensory input dictates that the brain must prioritize and select information for further processing and storage in working memory. Stimulus salience and reward expectations influence this prioritization but their relative contributions and underlying mechanisms are poorly un...

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Autores principales:	P. Christiaan Klink, Danique Jeurissen, Jan Theeuwes, Damiaan Denys, Pieter R. Roelfsema
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8e8a04369b4f473c9363046b598e27e8
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spelling	oai:doaj.org-article:8e8a04369b4f473c9363046b598e27e82021-12-02T15:05:06ZWorking memory accuracy for multiple targets is driven by reward expectation and stimulus contrast with different time-courses10.1038/s41598-017-08608-42045-2322https://doaj.org/article/8e8a04369b4f473c9363046b598e27e82017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-08608-4https://doaj.org/toc/2045-2322Abstract The richness of sensory input dictates that the brain must prioritize and select information for further processing and storage in working memory. Stimulus salience and reward expectations influence this prioritization but their relative contributions and underlying mechanisms are poorly understood. Here we investigate how the quality of working memory for multiple stimuli is determined by priority during encoding and later memory phases. Selective attention could, for instance, act as the primary gating mechanism when stimuli are still visible. Alternatively, observers might still be able to shift priorities across memories during maintenance or retrieval. To distinguish between these possibilities, we investigated how and when reward cues determine working memory accuracy and found that they were only effective during memory encoding. Previously learned, but currently non-predictive, color-reward associations had a similar influence, which gradually weakened without reinforcement. Finally, we show that bottom-up salience, manipulated through varying stimulus contrast, influences memory accuracy during encoding with a fundamentally different time-course than top-down reward cues. While reward-based effects required long stimulus presentation, the influence of contrast was strongest with brief presentations. Our results demonstrate how memory resources are distributed over memory targets and implicates selective attention as a main gating mechanism between sensory and memory systems.P. Christiaan KlinkDanique JeurissenJan TheeuwesDamiaan DenysPieter R. RoelfsemaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q P. Christiaan Klink Danique Jeurissen Jan Theeuwes Damiaan Denys Pieter R. Roelfsema Working memory accuracy for multiple targets is driven by reward expectation and stimulus contrast with different time-courses
description	Abstract The richness of sensory input dictates that the brain must prioritize and select information for further processing and storage in working memory. Stimulus salience and reward expectations influence this prioritization but their relative contributions and underlying mechanisms are poorly understood. Here we investigate how the quality of working memory for multiple stimuli is determined by priority during encoding and later memory phases. Selective attention could, for instance, act as the primary gating mechanism when stimuli are still visible. Alternatively, observers might still be able to shift priorities across memories during maintenance or retrieval. To distinguish between these possibilities, we investigated how and when reward cues determine working memory accuracy and found that they were only effective during memory encoding. Previously learned, but currently non-predictive, color-reward associations had a similar influence, which gradually weakened without reinforcement. Finally, we show that bottom-up salience, manipulated through varying stimulus contrast, influences memory accuracy during encoding with a fundamentally different time-course than top-down reward cues. While reward-based effects required long stimulus presentation, the influence of contrast was strongest with brief presentations. Our results demonstrate how memory resources are distributed over memory targets and implicates selective attention as a main gating mechanism between sensory and memory systems.
format	article
author	P. Christiaan Klink Danique Jeurissen Jan Theeuwes Damiaan Denys Pieter R. Roelfsema
author_facet	P. Christiaan Klink Danique Jeurissen Jan Theeuwes Damiaan Denys Pieter R. Roelfsema
author_sort	P. Christiaan Klink
title	Working memory accuracy for multiple targets is driven by reward expectation and stimulus contrast with different time-courses
title_short	Working memory accuracy for multiple targets is driven by reward expectation and stimulus contrast with different time-courses
title_full	Working memory accuracy for multiple targets is driven by reward expectation and stimulus contrast with different time-courses
title_fullStr	Working memory accuracy for multiple targets is driven by reward expectation and stimulus contrast with different time-courses
title_full_unstemmed	Working memory accuracy for multiple targets is driven by reward expectation and stimulus contrast with different time-courses
title_sort	working memory accuracy for multiple targets is driven by reward expectation and stimulus contrast with different time-courses
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/8e8a04369b4f473c9363046b598e27e8
work_keys_str_mv	AT pchristiaanklink workingmemoryaccuracyformultipletargetsisdrivenbyrewardexpectationandstimuluscontrastwithdifferenttimecourses AT daniquejeurissen workingmemoryaccuracyformultipletargetsisdrivenbyrewardexpectationandstimuluscontrastwithdifferenttimecourses AT jantheeuwes workingmemoryaccuracyformultipletargetsisdrivenbyrewardexpectationandstimuluscontrastwithdifferenttimecourses AT damiaandenys workingmemoryaccuracyformultipletargetsisdrivenbyrewardexpectationandstimuluscontrastwithdifferenttimecourses AT pieterrroelfsema workingmemoryaccuracyformultipletargetsisdrivenbyrewardexpectationandstimuluscontrastwithdifferenttimecourses
_version_	1718388969085861888

Working memory accuracy for multiple targets is driven by reward expectation and stimulus contrast with different time-courses

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