Recombinant Thrombomodulin Exerts Anti-autophagic Action in Endothelial Cells and Provides Anti-atherosclerosis Effect in Apolipoprotein E Deficient Mice
Abstract Stress-induced alteration in endothelial cells (ECs) integrity precedes the development of atherosclerosis. Previous studies showed that the soluble recombinant thrombomodulin (rTM) not only increases ECs proliferation but also exerts anti-apoptotic activity in ECs. However, the functional...
Enregistré dans:
Auteurs principaux: | Po-Sheng Chen, Kuan-Chieh Wang, Ting-Hsing Chao, Hsing-Chun Chung, Shi-Ya Tseng, Chawn-Yau Luo, Guey-Yueh Shi, Hua-Lin Wu, Yi-Heng Li |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/8e8dabad06ad4d79a6b1dbca4e9c35df |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Association of thrombomodulin Ala455Val dimorphism and inflammatory cytokines with carotid atherosclerosis in the Chinese Han population
par: Qian G, et autres
Publié: (2012) -
Inhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cells.
par: Johannes Klose, et autres
Publié: (2014) -
Thrombomodulin is upregulated in the kidneys of women with pre-eclampsia
par: Cleo C. L. van Aanhold, et autres
Publié: (2021) -
The Tnfaip8-PE complex is a novel upstream effector in the anti-autophagic action of insulin
par: Ji-Soo Kim, et autres
Publié: (2017) -
Curcumin and Radiotherapy Exert Synergistic Anti-Glioma Effect In Vitro
par: Vasiliki Zoi, et autres
Publié: (2021)