Emerging therapies for treatment of multiple sclerosis

John R Corboy, Augusto A MiravalleRocky Mountain Multiple Sclerosis Center, Anschutz Medical Campus, University of Colorado Denver, Aurora, Colorado, USAAbstract: In the last decade, a new armamentarium of immune-based therapies have been developed and tested in patients with multiple sclerosis. Som...

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Main Authors:	John R Corboy, Augusto A Miravalle
Format:	article
Language:	EN
Published:	Dove Medical Press 2010
Subjects:	Pathology RB1-214 Therapeutics. Pharmacology RM1-950
Online Access:	https://doaj.org/article/8e9a9038c8bc4f2da5dd14a4a4fedb5b
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id	oai:doaj.org-article:8e9a9038c8bc4f2da5dd14a4a4fedb5b
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spelling	oai:doaj.org-article:8e9a9038c8bc4f2da5dd14a4a4fedb5b2021-12-02T02:11:56ZEmerging therapies for treatment of multiple sclerosis1178-7031https://doaj.org/article/8e9a9038c8bc4f2da5dd14a4a4fedb5b2010-07-01T00:00:00Zhttp://www.dovepress.com/emerging-therapies-for-treatment-of-multiple-sclerosis-a4898https://doaj.org/toc/1178-7031John R Corboy, Augusto A MiravalleRocky Mountain Multiple Sclerosis Center, Anschutz Medical Campus, University of Colorado Denver, Aurora, Colorado, USAAbstract: In the last decade, a new armamentarium of immune-based therapies have been developed and tested in patients with multiple sclerosis. Some of these therapies are showing a high level of efficacy, with an acceptable adverse effect profile. Because present therapies have significant limitations in slowing disease progression, require injections, are sometimes associated with significant side effects of immunosuppression, and do little to reverse disability, identifying more effective treatments is an important goal for clinical research in multiple sclerosis. However, in order to improve our current approach to disease-modifying therapies, it is imperative to promote the development of individualized therapy strategies.Keywords: multiple sclerosis, lymphocyte-targeted therapy, immune sequestration, non-specific immune modulation John R CorboyAugusto A MiravalleDove Medical PressarticlePathologyRB1-214Therapeutics. PharmacologyRM1-950ENJournal of Inflammation Research, Vol 2010, Iss default, Pp 53-59 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Pathology RB1-214 Therapeutics. Pharmacology RM1-950
spellingShingle	Pathology RB1-214 Therapeutics. Pharmacology RM1-950 John R Corboy Augusto A Miravalle Emerging therapies for treatment of multiple sclerosis
description	John R Corboy, Augusto A MiravalleRocky Mountain Multiple Sclerosis Center, Anschutz Medical Campus, University of Colorado Denver, Aurora, Colorado, USAAbstract: In the last decade, a new armamentarium of immune-based therapies have been developed and tested in patients with multiple sclerosis. Some of these therapies are showing a high level of efficacy, with an acceptable adverse effect profile. Because present therapies have significant limitations in slowing disease progression, require injections, are sometimes associated with significant side effects of immunosuppression, and do little to reverse disability, identifying more effective treatments is an important goal for clinical research in multiple sclerosis. However, in order to improve our current approach to disease-modifying therapies, it is imperative to promote the development of individualized therapy strategies.Keywords: multiple sclerosis, lymphocyte-targeted therapy, immune sequestration, non-specific immune modulation
format	article
author	John R Corboy Augusto A Miravalle
author_facet	John R Corboy Augusto A Miravalle
author_sort	John R Corboy
title	Emerging therapies for treatment of multiple sclerosis
title_short	Emerging therapies for treatment of multiple sclerosis
title_full	Emerging therapies for treatment of multiple sclerosis
title_fullStr	Emerging therapies for treatment of multiple sclerosis
title_full_unstemmed	Emerging therapies for treatment of multiple sclerosis
title_sort	emerging therapies for treatment of multiple sclerosis
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/8e9a9038c8bc4f2da5dd14a4a4fedb5b
work_keys_str_mv	AT johnrcorboy emergingtherapiesfortreatmentofmultiplesclerosis AT augustoamiravalle emergingtherapiesfortreatmentofmultiplesclerosis
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Emerging therapies for treatment of multiple sclerosis

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