Translating Psychedelic Therapies From Clinical Trials to Community Clinics: Building Bridges and Addressing Potential Challenges Ahead

Research exploring the potential of psychedelic-assisted therapies to treat a range of mental illnesses is flourishing, after the problematic sociopolitical history of psychedelics led to the shutdown of clinical research for almost 40 years. Encouraged by positive results, clinicians and patients a...

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Autores principales: Martin L. Williams, Diana Korevaar, Renee Harvey, Paul B. Fitzgerald, Paul Liknaitzky, Sean O'Carroll, Prashanth Puspanathan, Margaret Ross, Nigel Strauss, James Bennett-Levy
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Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/8ebc93b13d294a1a9d79debad29b087f
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spelling oai:doaj.org-article:8ebc93b13d294a1a9d79debad29b087f2021-11-04T05:36:46ZTranslating Psychedelic Therapies From Clinical Trials to Community Clinics: Building Bridges and Addressing Potential Challenges Ahead1664-064010.3389/fpsyt.2021.737738https://doaj.org/article/8ebc93b13d294a1a9d79debad29b087f2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fpsyt.2021.737738/fullhttps://doaj.org/toc/1664-0640Research exploring the potential of psychedelic-assisted therapies to treat a range of mental illnesses is flourishing, after the problematic sociopolitical history of psychedelics led to the shutdown of clinical research for almost 40 years. Encouraged by positive results, clinicians and patients are now hopeful that further interruptions to research will be avoided, so that the early promise of these therapies might be fulfilled. At this early stage of renewed interest, researchers are understandably focusing more on clinical trials to investigate safety and efficacy, than on longer-term goals such as progression to community practice. Looking to identify and avoid potential pitfalls on the path to community clinics, the authors, a group of Australian clinicians and researchers, met to discuss possible obstacles. Five broad categories of challenge were identified: 1) inherent risks; 2) poor clinical practice; 3) inadequate infrastructure; 4) problematic perceptions; and 5) divisive relationships and fractionation of the field. Our analysis led us to propose some strategies, including public sector support of research and training to establish best practice and optimize translation, and funding to address issues of equitable access to treatment. Above all, we believe that strategic planning and professional cohesion will be crucial for success. Accordingly, our key recommendation is the establishment of a multidisciplinary advisory body, broadly endorsed and representing all major stakeholders, to guide policy and implementation of psychedelic-assisted therapies in Australia. Although these challenges and strategies are framed within the Australian context, we sense that they may generalize to other parts of the world. Wherever they apply, we believe that anticipation of potential difficulties, and creative responses to address them, will be important to avoid roadblocks in the future and keep the “psychedelic renaissance” on track.Martin L. WilliamsMartin L. WilliamsDiana KorevaarDiana KorevaarRenee HarveyPaul B. FitzgeraldPaul B. FitzgeraldPaul LiknaitzkyPaul LiknaitzkySean O'CarrollPrashanth PuspanathanMargaret RossNigel StraussNigel StraussNigel StraussJames Bennett-LevyFrontiers Media S.A.articlepsychedelicsmental healthclinical researchtranslationcommunity clinicspsilocybinPsychiatryRC435-571ENFrontiers in Psychiatry, Vol 12 (2021)
institution DOAJ
collection DOAJ
language EN
topic psychedelics
mental health
clinical research
translation
community clinics
psilocybin
Psychiatry
RC435-571
spellingShingle psychedelics
mental health
clinical research
translation
community clinics
psilocybin
Psychiatry
RC435-571
Martin L. Williams
Martin L. Williams
Diana Korevaar
Diana Korevaar
Renee Harvey
Paul B. Fitzgerald
Paul B. Fitzgerald
Paul Liknaitzky
Paul Liknaitzky
Sean O'Carroll
Prashanth Puspanathan
Margaret Ross
Nigel Strauss
Nigel Strauss
Nigel Strauss
James Bennett-Levy
Translating Psychedelic Therapies From Clinical Trials to Community Clinics: Building Bridges and Addressing Potential Challenges Ahead
description Research exploring the potential of psychedelic-assisted therapies to treat a range of mental illnesses is flourishing, after the problematic sociopolitical history of psychedelics led to the shutdown of clinical research for almost 40 years. Encouraged by positive results, clinicians and patients are now hopeful that further interruptions to research will be avoided, so that the early promise of these therapies might be fulfilled. At this early stage of renewed interest, researchers are understandably focusing more on clinical trials to investigate safety and efficacy, than on longer-term goals such as progression to community practice. Looking to identify and avoid potential pitfalls on the path to community clinics, the authors, a group of Australian clinicians and researchers, met to discuss possible obstacles. Five broad categories of challenge were identified: 1) inherent risks; 2) poor clinical practice; 3) inadequate infrastructure; 4) problematic perceptions; and 5) divisive relationships and fractionation of the field. Our analysis led us to propose some strategies, including public sector support of research and training to establish best practice and optimize translation, and funding to address issues of equitable access to treatment. Above all, we believe that strategic planning and professional cohesion will be crucial for success. Accordingly, our key recommendation is the establishment of a multidisciplinary advisory body, broadly endorsed and representing all major stakeholders, to guide policy and implementation of psychedelic-assisted therapies in Australia. Although these challenges and strategies are framed within the Australian context, we sense that they may generalize to other parts of the world. Wherever they apply, we believe that anticipation of potential difficulties, and creative responses to address them, will be important to avoid roadblocks in the future and keep the “psychedelic renaissance” on track.
format article
author Martin L. Williams
Martin L. Williams
Diana Korevaar
Diana Korevaar
Renee Harvey
Paul B. Fitzgerald
Paul B. Fitzgerald
Paul Liknaitzky
Paul Liknaitzky
Sean O'Carroll
Prashanth Puspanathan
Margaret Ross
Nigel Strauss
Nigel Strauss
Nigel Strauss
James Bennett-Levy
author_facet Martin L. Williams
Martin L. Williams
Diana Korevaar
Diana Korevaar
Renee Harvey
Paul B. Fitzgerald
Paul B. Fitzgerald
Paul Liknaitzky
Paul Liknaitzky
Sean O'Carroll
Prashanth Puspanathan
Margaret Ross
Nigel Strauss
Nigel Strauss
Nigel Strauss
James Bennett-Levy
author_sort Martin L. Williams
title Translating Psychedelic Therapies From Clinical Trials to Community Clinics: Building Bridges and Addressing Potential Challenges Ahead
title_short Translating Psychedelic Therapies From Clinical Trials to Community Clinics: Building Bridges and Addressing Potential Challenges Ahead
title_full Translating Psychedelic Therapies From Clinical Trials to Community Clinics: Building Bridges and Addressing Potential Challenges Ahead
title_fullStr Translating Psychedelic Therapies From Clinical Trials to Community Clinics: Building Bridges and Addressing Potential Challenges Ahead
title_full_unstemmed Translating Psychedelic Therapies From Clinical Trials to Community Clinics: Building Bridges and Addressing Potential Challenges Ahead
title_sort translating psychedelic therapies from clinical trials to community clinics: building bridges and addressing potential challenges ahead
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/8ebc93b13d294a1a9d79debad29b087f
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