Optimized In Silico Modeling of Drug Absorption after Gastric Bypass: The Case of Metformin

Bariatric surgery is an effective treatment for severe obesity and related comorbidities, such as type II diabetes. Gastric bypass surgery shortens the length of the intestine, possibly leading to altered drug absorption. Metformin, a first-line treatment for type II diabetes, has permeability-depen...

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Auteurs principaux: Arik Dahan, Daniel Porat, Milica Markovic, Moran Zur, Olga Kister, Peter Langguth
Format: article
Langue:EN
Publié: MDPI AG 2021
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Accès en ligne:https://doaj.org/article/8ebf2fb240e84f12ad8b7c8d56b0e37c
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