TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammation.
TRPM2, a highly Ca(2+)-permeable member of the transient receptor potential melastatin-related (TRPM) family of cation channels, is expressed in cells of the immune system. We demonstrate firstly that TRPM2 cation channels on T cells critically influence T cell proliferation and proinflammatory cyto...
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Autores principales: | Nico Melzer, Gordon Hicking, Kerstin Göbel, Heinz Wiendl |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/8ec43f6a7756479ab0d4eddd781a2f08 |
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