TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammation.

TRPM2, a highly Ca(2+)-permeable member of the transient receptor potential melastatin-related (TRPM) family of cation channels, is expressed in cells of the immune system. We demonstrate firstly that TRPM2 cation channels on T cells critically influence T cell proliferation and proinflammatory cyto...

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Bibliographic Details
Main Authors: Nico Melzer, Gordon Hicking, Kerstin Göbel, Heinz Wiendl
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
R
Q
Online Access:https://doaj.org/article/8ec43f6a7756479ab0d4eddd781a2f08
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