Flexible, sticky, and biodegradable wireless device for drug delivery to brain tumors

There is a need to further improve the efficacy of biodegradable wafers used in surgically treated brain tumors. Here, the authors report a flexible, biodegradable wireless device capable of adhesion to surgical site for optimal drug delivery upon mild-thermic actuation and report therapeutic effica...

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Autores principales: Jongha Lee, Hye Rim Cho, Gi Doo Cha, Hyunseon Seo, Seunghyun Lee, Chul-Kee Park, Jin Wook Kim, Shutao Qiao, Liu Wang, Dayoung Kang, Taegyu Kang, Tomotsugu Ichikawa, Jonghoon Kim, Hakyong Lee, Woongchan Lee, Sanghoek Kim, Soon-Tae Lee, Nanshu Lu, Taeghwan Hyeon, Seung Hong Choi, Dae-Hyeong Kim
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/8ed7fe9321a6430ea66d3a31f1574f0e
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spelling oai:doaj.org-article:8ed7fe9321a6430ea66d3a31f1574f0e2021-12-02T15:35:10ZFlexible, sticky, and biodegradable wireless device for drug delivery to brain tumors10.1038/s41467-019-13198-y2041-1723https://doaj.org/article/8ed7fe9321a6430ea66d3a31f1574f0e2019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13198-yhttps://doaj.org/toc/2041-1723There is a need to further improve the efficacy of biodegradable wafers used in surgically treated brain tumors. Here, the authors report a flexible, biodegradable wireless device capable of adhesion to surgical site for optimal drug delivery upon mild-thermic actuation and report therapeutic efficacy in mouse and canine tumor models.Jongha LeeHye Rim ChoGi Doo ChaHyunseon SeoSeunghyun LeeChul-Kee ParkJin Wook KimShutao QiaoLiu WangDayoung KangTaegyu KangTomotsugu IchikawaJonghoon KimHakyong LeeWoongchan LeeSanghoek KimSoon-Tae LeeNanshu LuTaeghwan HyeonSeung Hong ChoiDae-Hyeong KimNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jongha Lee
Hye Rim Cho
Gi Doo Cha
Hyunseon Seo
Seunghyun Lee
Chul-Kee Park
Jin Wook Kim
Shutao Qiao
Liu Wang
Dayoung Kang
Taegyu Kang
Tomotsugu Ichikawa
Jonghoon Kim
Hakyong Lee
Woongchan Lee
Sanghoek Kim
Soon-Tae Lee
Nanshu Lu
Taeghwan Hyeon
Seung Hong Choi
Dae-Hyeong Kim
Flexible, sticky, and biodegradable wireless device for drug delivery to brain tumors
description There is a need to further improve the efficacy of biodegradable wafers used in surgically treated brain tumors. Here, the authors report a flexible, biodegradable wireless device capable of adhesion to surgical site for optimal drug delivery upon mild-thermic actuation and report therapeutic efficacy in mouse and canine tumor models.
format article
author Jongha Lee
Hye Rim Cho
Gi Doo Cha
Hyunseon Seo
Seunghyun Lee
Chul-Kee Park
Jin Wook Kim
Shutao Qiao
Liu Wang
Dayoung Kang
Taegyu Kang
Tomotsugu Ichikawa
Jonghoon Kim
Hakyong Lee
Woongchan Lee
Sanghoek Kim
Soon-Tae Lee
Nanshu Lu
Taeghwan Hyeon
Seung Hong Choi
Dae-Hyeong Kim
author_facet Jongha Lee
Hye Rim Cho
Gi Doo Cha
Hyunseon Seo
Seunghyun Lee
Chul-Kee Park
Jin Wook Kim
Shutao Qiao
Liu Wang
Dayoung Kang
Taegyu Kang
Tomotsugu Ichikawa
Jonghoon Kim
Hakyong Lee
Woongchan Lee
Sanghoek Kim
Soon-Tae Lee
Nanshu Lu
Taeghwan Hyeon
Seung Hong Choi
Dae-Hyeong Kim
author_sort Jongha Lee
title Flexible, sticky, and biodegradable wireless device for drug delivery to brain tumors
title_short Flexible, sticky, and biodegradable wireless device for drug delivery to brain tumors
title_full Flexible, sticky, and biodegradable wireless device for drug delivery to brain tumors
title_fullStr Flexible, sticky, and biodegradable wireless device for drug delivery to brain tumors
title_full_unstemmed Flexible, sticky, and biodegradable wireless device for drug delivery to brain tumors
title_sort flexible, sticky, and biodegradable wireless device for drug delivery to brain tumors
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/8ed7fe9321a6430ea66d3a31f1574f0e
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