The Triangulation WIthin a STudy (TWIST) framework for causal inference within pharmacogenetic research.

In this paper we review the methodological underpinnings of the general pharmacogenetic approach for uncovering genetically-driven treatment effect heterogeneity. This typically utilises only individuals who are treated and relies on fairly strong baseline assumptions to estimate what we term the &#...

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Bibliographic Details
Main Authors: Jack Bowden, Luke C Pilling, Deniz Türkmen, Chia-Ling Kuo, David Melzer
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
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Online Access:https://doaj.org/article/8edadb6867a74942bd7f7485670e41c3
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