The Triangulation WIthin a STudy (TWIST) framework for causal inference within pharmacogenetic research.
In this paper we review the methodological underpinnings of the general pharmacogenetic approach for uncovering genetically-driven treatment effect heterogeneity. This typically utilises only individuals who are treated and relies on fairly strong baseline assumptions to estimate what we term the ...
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Main Authors: | , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
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Subjects: | |
Online Access: | https://doaj.org/article/8edadb6867a74942bd7f7485670e41c3 |
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