EXPERIMENTAL STUDIES OF THE SPECIFICITY OF IMMUNE RESPONSE IN VARIOUS OCCUPATIONAL DISEASES

Experimental models of anthracosilicosis (AS) and fluoride intoxication. (FI) show that the inhalation of coal and. rock dust (CRD) results in an early anti-inflammatory cytokine response (IL-4, IL-10) and. activation of humoral immunity on the background of lower level of proinflammatory cytokines....

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Autores principales: D. V. Fomenko, N. N. Mikhailova, A. S. Kazitskya, E. V. Ulanova, Y. A. Prokopyev
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2012
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Acceso en línea:https://doaj.org/article/8ee813c0f5ae4777b312126f77c5286e
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spelling oai:doaj.org-article:8ee813c0f5ae4777b312126f77c5286e2021-11-23T06:14:25ZEXPERIMENTAL STUDIES OF THE SPECIFICITY OF IMMUNE RESPONSE IN VARIOUS OCCUPATIONAL DISEASES2541-94202587-9596https://doaj.org/article/8ee813c0f5ae4777b312126f77c5286e2012-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1205https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Experimental models of anthracosilicosis (AS) and fluoride intoxication. (FI) show that the inhalation of coal and. rock dust (CRD) results in an early anti-inflammatory cytokine response (IL-4, IL-10) and. activation of humoral immunity on the background of lower level of proinflammatory cytokines. Later stages of the CRD activity are characterized by inflammation and. immunodeficiency. FI start is accompanied, by an increase of proinflammatory cytokines (IL-8, TNF-α). Anti-inflammatory protection is seen on the later stages (IL-10), immunoglobulin levels did. not change during 6 weeks of FI. Recommendations for the prevention of the anthracosilicosis and. fluoride intoxication given.D. V. FomenkoN. N. MikhailovaA. S. KazitskyaE. V. UlanovaY. A. ProkopyevScientific Сentre for Family Health and Human Reproduction Problemsarticleanthracosilicosisfluoride intoxicationcytokinesimmunoglobulinsScienceQRUActa Biomedica Scientifica, Vol 0, Iss 5(2), Pp 115-119 (2012)
institution DOAJ
collection DOAJ
language RU
topic anthracosilicosis
fluoride intoxication
cytokines
immunoglobulins
Science
Q
spellingShingle anthracosilicosis
fluoride intoxication
cytokines
immunoglobulins
Science
Q
D. V. Fomenko
N. N. Mikhailova
A. S. Kazitskya
E. V. Ulanova
Y. A. Prokopyev
EXPERIMENTAL STUDIES OF THE SPECIFICITY OF IMMUNE RESPONSE IN VARIOUS OCCUPATIONAL DISEASES
description Experimental models of anthracosilicosis (AS) and fluoride intoxication. (FI) show that the inhalation of coal and. rock dust (CRD) results in an early anti-inflammatory cytokine response (IL-4, IL-10) and. activation of humoral immunity on the background of lower level of proinflammatory cytokines. Later stages of the CRD activity are characterized by inflammation and. immunodeficiency. FI start is accompanied, by an increase of proinflammatory cytokines (IL-8, TNF-α). Anti-inflammatory protection is seen on the later stages (IL-10), immunoglobulin levels did. not change during 6 weeks of FI. Recommendations for the prevention of the anthracosilicosis and. fluoride intoxication given.
format article
author D. V. Fomenko
N. N. Mikhailova
A. S. Kazitskya
E. V. Ulanova
Y. A. Prokopyev
author_facet D. V. Fomenko
N. N. Mikhailova
A. S. Kazitskya
E. V. Ulanova
Y. A. Prokopyev
author_sort D. V. Fomenko
title EXPERIMENTAL STUDIES OF THE SPECIFICITY OF IMMUNE RESPONSE IN VARIOUS OCCUPATIONAL DISEASES
title_short EXPERIMENTAL STUDIES OF THE SPECIFICITY OF IMMUNE RESPONSE IN VARIOUS OCCUPATIONAL DISEASES
title_full EXPERIMENTAL STUDIES OF THE SPECIFICITY OF IMMUNE RESPONSE IN VARIOUS OCCUPATIONAL DISEASES
title_fullStr EXPERIMENTAL STUDIES OF THE SPECIFICITY OF IMMUNE RESPONSE IN VARIOUS OCCUPATIONAL DISEASES
title_full_unstemmed EXPERIMENTAL STUDIES OF THE SPECIFICITY OF IMMUNE RESPONSE IN VARIOUS OCCUPATIONAL DISEASES
title_sort experimental studies of the specificity of immune response in various occupational diseases
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2012
url https://doaj.org/article/8ee813c0f5ae4777b312126f77c5286e
work_keys_str_mv AT dvfomenko experimentalstudiesofthespecificityofimmuneresponseinvariousoccupationaldiseases
AT nnmikhailova experimentalstudiesofthespecificityofimmuneresponseinvariousoccupationaldiseases
AT askazitskya experimentalstudiesofthespecificityofimmuneresponseinvariousoccupationaldiseases
AT evulanova experimentalstudiesofthespecificityofimmuneresponseinvariousoccupationaldiseases
AT yaprokopyev experimentalstudiesofthespecificityofimmuneresponseinvariousoccupationaldiseases
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