Conditional RAC1 knockout in motor neurons restores H-reflex rate-dependent depression after spinal cord injury

Conditional RAC1 knockout in motor neurons restores H-reflex rate-dependent depression after spinal cord injury

Abstract A major complication with spinal cord injury (SCI) is the development of spasticity, a clinical symptom of hyperexcitability within the spinal H-reflex pathway. We have previously demonstrated a common structural motif of dendritic spine dysgenesis associated with hyperexcitability disorder...

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Bibliographic Details
Main Authors: Curtis A. Benson, Kai-Lan Olson, Siraj Patwa, Marike L. Reimer, Lakshmi Bangalore, Myriam Hill, Stephen G. Waxman, Andrew M. Tan
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/8eead8da8f334be583b42fdfcc67a7df
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