eIF2α signaling regulates ischemic osteonecrosis through endoplasmic reticulum stress

eIF2α signaling regulates ischemic osteonecrosis through endoplasmic reticulum stress

Abstract Osteonecrosis of the femoral head (ONFH) primarily results from ischemia/hypoxia to the femoral head, and one of the cellular manifestations is the endoplasmic reticulum (ER) stress. To understand possible linkage of ischemic osteonecrosis to the ER stress, a surgery-induced animal model wa...

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Autores principales: Daquan Liu, Yunlong Zhang, Xinle Li, Jie Li, Shuang Yang, Xiaoxue Xing, Guanwei Fan, Hiroki Yokota, Ping Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/8eec0e8f41b8472a8778f0f1919533e3
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