Genetic Stabilization of the Drug-Resistant PMEN1 Pneumococcus Lineage by Its Distinctive DpnIII Restriction-Modification System

ABSTRACT The human pathogen Streptococcus pneumoniae (pneumococcus) exhibits a high degree of genomic diversity and plasticity. Isolates with high genomic similarity are grouped into lineages that undergo homologous recombination at variable rates. PMEN1 is a pandemic, multidrug-resistant lineage. H...

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Main Authors: Rory A. Eutsey, Evan Powell, Janina Dordel, Susannah J. Salter, Tyson A. Clark, Jonas Korlach, Garth D. Ehrlich, N. Luisa Hiller
Format: article
Language:EN
Published: American Society for Microbiology 2015
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Online Access:https://doaj.org/article/8efb1484f36b4fb2aeee87b5b10d03d3
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