Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus

<i>Background and Objectives</i>: Gestational diabetes mellitus (GDM) represents one of the most common complications during pregnancy, being associated with numerous maternal and neonatal complications. The study aimed to analyze maternal and neonatal complications associated with GDM....

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Autores principales:	Agnesa Preda, Vlad Pădureanu, Maria Moța, Adela-Gabriela Ștefan, Alexandru Cristian Comănescu, Lucrețiu Radu, Emilia Roxana Mazilu, Ionela Mihaela Vladu
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	pregnancy gestational diabetes mellitus maternal complications neonatal complications Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/8f06efc9ba2d4a46918b584d24046d52
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spelling	oai:doaj.org-article:8f06efc9ba2d4a46918b584d24046d522021-11-25T18:18:17ZAnalysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus10.3390/medicina571111701648-91441010-660Xhttps://doaj.org/article/8f06efc9ba2d4a46918b584d24046d522021-10-01T00:00:00Zhttps://www.mdpi.com/1648-9144/57/11/1170https://doaj.org/toc/1010-660Xhttps://doaj.org/toc/1648-9144<i>Background and Objectives</i>: Gestational diabetes mellitus (GDM) represents one of the most common complications during pregnancy, being associated with numerous maternal and neonatal complications. The study aimed to analyze maternal and neonatal complications associated with GDM. The risk factors of GDM and of the maternal and neonatal complications were studied in order to prevent their occurrence. <i>Materials and Methods</i>: The study included 97 women in the study, who underwent an oral glucose tolerance test (OGTT) between weeks 24–28 of pregnancy, consequently being divided into two groups: pregnant women with and without GDM. Statistical analysis was performed using the SPSS 26.0 software and MATLAB fitglm, the results being considered statistically significant if <i>p</i> < 0.05. <i>Results</i>: We observed statistically significant differences between the group of women with and without GDM, regarding gestational hypertension (17.6% vs. 0%), preeclampsia (13.72% vs. 0%), and cesarean delivery (96.1% vs. 78,3%). Data on the newborn and neonatal complications: statistically significant differences were recorded between the two groups (GDM vs. no GDM) regarding the average weight at birth (3339.41 ± 658.12 g vs. 3122.83 ± 173.67 g), presence of large for gestational age (21.6% vs. 0%), macrosomia (13.7% vs. 0%), excessive fetal growth (35.3% vs. 0%), respiratory distress (31.4% vs. 0%), hospitalization for at least 24 h in the Neonatal Intensive Care Unit (9.80% vs. 0%), and APGAR score <7 both 1 and 5 min following birth (7.8% vs. 0%). Additionally, the frequency of neonatal hypoglycemia and hyperbilirubinemia was higher among newborns from mothers with GDM. <i>Conclusions:</i> The screening and diagnosis of GDM is vital, and appropriate management is required for the prevention of maternal and neonatal complications associated with GDM. It is also important to know the risk factors for GDM and attempt to prevent their appearance.Agnesa PredaVlad PădureanuMaria MoțaAdela-Gabriela ȘtefanAlexandru Cristian ComănescuLucrețiu RaduEmilia Roxana MaziluIonela Mihaela VladuMDPI AGarticlepregnancygestational diabetes mellitusmaternal complicationsneonatal complicationsMedicine (General)R5-920ENMedicina, Vol 57, Iss 1170, p 1170 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	pregnancy gestational diabetes mellitus maternal complications neonatal complications Medicine (General) R5-920
spellingShingle	pregnancy gestational diabetes mellitus maternal complications neonatal complications Medicine (General) R5-920 Agnesa Preda Vlad Pădureanu Maria Moța Adela-Gabriela Ștefan Alexandru Cristian Comănescu Lucrețiu Radu Emilia Roxana Mazilu Ionela Mihaela Vladu Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus
description	<i>Background and Objectives</i>: Gestational diabetes mellitus (GDM) represents one of the most common complications during pregnancy, being associated with numerous maternal and neonatal complications. The study aimed to analyze maternal and neonatal complications associated with GDM. The risk factors of GDM and of the maternal and neonatal complications were studied in order to prevent their occurrence. <i>Materials and Methods</i>: The study included 97 women in the study, who underwent an oral glucose tolerance test (OGTT) between weeks 24–28 of pregnancy, consequently being divided into two groups: pregnant women with and without GDM. Statistical analysis was performed using the SPSS 26.0 software and MATLAB fitglm, the results being considered statistically significant if <i>p</i> < 0.05. <i>Results</i>: We observed statistically significant differences between the group of women with and without GDM, regarding gestational hypertension (17.6% vs. 0%), preeclampsia (13.72% vs. 0%), and cesarean delivery (96.1% vs. 78,3%). Data on the newborn and neonatal complications: statistically significant differences were recorded between the two groups (GDM vs. no GDM) regarding the average weight at birth (3339.41 ± 658.12 g vs. 3122.83 ± 173.67 g), presence of large for gestational age (21.6% vs. 0%), macrosomia (13.7% vs. 0%), excessive fetal growth (35.3% vs. 0%), respiratory distress (31.4% vs. 0%), hospitalization for at least 24 h in the Neonatal Intensive Care Unit (9.80% vs. 0%), and APGAR score <7 both 1 and 5 min following birth (7.8% vs. 0%). Additionally, the frequency of neonatal hypoglycemia and hyperbilirubinemia was higher among newborns from mothers with GDM. <i>Conclusions:</i> The screening and diagnosis of GDM is vital, and appropriate management is required for the prevention of maternal and neonatal complications associated with GDM. It is also important to know the risk factors for GDM and attempt to prevent their appearance.
format	article
author	Agnesa Preda Vlad Pădureanu Maria Moța Adela-Gabriela Ștefan Alexandru Cristian Comănescu Lucrețiu Radu Emilia Roxana Mazilu Ionela Mihaela Vladu
author_facet	Agnesa Preda Vlad Pădureanu Maria Moța Adela-Gabriela Ștefan Alexandru Cristian Comănescu Lucrețiu Radu Emilia Roxana Mazilu Ionela Mihaela Vladu
author_sort	Agnesa Preda
title	Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus
title_short	Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus
title_full	Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus
title_fullStr	Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus
title_full_unstemmed	Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus
title_sort	analysis of maternal and neonatal complications in a group of patients with gestational diabetes mellitus
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/8f06efc9ba2d4a46918b584d24046d52
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Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus

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