Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities

Developing noninvasive diagnostic biomarkers for lupus nephritis (LN) diagnosis is an important clinical goal. Here the authors identify urinary proteins correlated with active LN and disease severity, which differ across ethnicities but collectively outperform the current clinical method.

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Autores principales:	Samantha Stanley, Kamala Vanarsa, Samar Soliman, Deena Habazi, Claudia Pedroza, Gabriel Gidley, Ting Zhang, Shree Mohan, Evan Der, Hemant Suryawanshi, Thomas Tuschl, Jill Buyon, Chaim Putterman, Chi Chiu Mok, Michelle Petri, Ramesh Saxena, Chandra Mohan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8f0c56b51da44a74acb2b59ce3524af9
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spelling	oai:doaj.org-article:8f0c56b51da44a74acb2b59ce3524af92021-12-02T16:49:27ZComprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities10.1038/s41467-020-15986-32041-1723https://doaj.org/article/8f0c56b51da44a74acb2b59ce3524af92020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15986-3https://doaj.org/toc/2041-1723Developing noninvasive diagnostic biomarkers for lupus nephritis (LN) diagnosis is an important clinical goal. Here the authors identify urinary proteins correlated with active LN and disease severity, which differ across ethnicities but collectively outperform the current clinical method.Samantha StanleyKamala VanarsaSamar SolimanDeena HabaziClaudia PedrozaGabriel GidleyTing ZhangShree MohanEvan DerHemant SuryawanshiThomas TuschlJill BuyonChaim PuttermanChi Chiu MokMichelle PetriRamesh SaxenaChandra MohanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Samantha Stanley Kamala Vanarsa Samar Soliman Deena Habazi Claudia Pedroza Gabriel Gidley Ting Zhang Shree Mohan Evan Der Hemant Suryawanshi Thomas Tuschl Jill Buyon Chaim Putterman Chi Chiu Mok Michelle Petri Ramesh Saxena Chandra Mohan Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities
description	Developing noninvasive diagnostic biomarkers for lupus nephritis (LN) diagnosis is an important clinical goal. Here the authors identify urinary proteins correlated with active LN and disease severity, which differ across ethnicities but collectively outperform the current clinical method.
format	article
author	Samantha Stanley Kamala Vanarsa Samar Soliman Deena Habazi Claudia Pedroza Gabriel Gidley Ting Zhang Shree Mohan Evan Der Hemant Suryawanshi Thomas Tuschl Jill Buyon Chaim Putterman Chi Chiu Mok Michelle Petri Ramesh Saxena Chandra Mohan
author_facet	Samantha Stanley Kamala Vanarsa Samar Soliman Deena Habazi Claudia Pedroza Gabriel Gidley Ting Zhang Shree Mohan Evan Der Hemant Suryawanshi Thomas Tuschl Jill Buyon Chaim Putterman Chi Chiu Mok Michelle Petri Ramesh Saxena Chandra Mohan
author_sort	Samantha Stanley
title	Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities
title_short	Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities
title_full	Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities
title_fullStr	Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities
title_full_unstemmed	Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities
title_sort	comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/8f0c56b51da44a74acb2b59ce3524af9
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Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities

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