Results of a German wide survey towards current surgical approach in early stage cervical cancer NOGGO MONITOR 11

Abstract Minimally invasive surgery (MIS) has become the standard approach in early stage cervical cancer (ECC). However, the recently published “LACC” trial and even others could show inferior PFS and OS of MIS compared to open radical hysterectomy. The results led to a widespread debate about the...

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Autores principales:	Robert Armbrust, Frank Chen, Rolf Richter, Mustafa Zela Muallem, Alexander Mustea, Bernd Holthaus, Jalid Sehouli
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8f0caa5d7d8347cf8d2da1eaf6c6811d
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spelling	oai:doaj.org-article:8f0caa5d7d8347cf8d2da1eaf6c6811d2021-12-02T14:41:52ZResults of a German wide survey towards current surgical approach in early stage cervical cancer NOGGO MONITOR 1110.1038/s41598-021-89071-02045-2322https://doaj.org/article/8f0caa5d7d8347cf8d2da1eaf6c6811d2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-89071-0https://doaj.org/toc/2045-2322Abstract Minimally invasive surgery (MIS) has become the standard approach in early stage cervical cancer (ECC). However, the recently published “LACC” trial and even others could show inferior PFS and OS of MIS compared to open radical hysterectomy. The results led to a widespread debate about the best surgical approach in ECC. The present survey aimed to get first insights after publication. NOGGO and AGE conducted a nationwide digital survey among 186 Gynecological Cancer Centers. Descriptive statistics and t-tests were performed using SPSS. A majority of the centers were of high expertise and/or experience in treatment of ECC and were highly aware of the LACC trial results. Trial quality and scientific value were rated as very good/good. However, still 40% would not change the standard of care to open surgery. Centers with higher volume and participating in clinical trials were more likely to change. This survey represents insights after the surprising results of recently published trials towards the surgical approach of ECC. There still seems to be a high need of future trials and possible explanations for the unexpected worse outcomes in the MIS group.Robert ArmbrustFrank ChenRolf RichterMustafa Zela MuallemAlexander MusteaBernd HolthausJalid SehouliNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Robert Armbrust Frank Chen Rolf Richter Mustafa Zela Muallem Alexander Mustea Bernd Holthaus Jalid Sehouli Results of a German wide survey towards current surgical approach in early stage cervical cancer NOGGO MONITOR 11
description	Abstract Minimally invasive surgery (MIS) has become the standard approach in early stage cervical cancer (ECC). However, the recently published “LACC” trial and even others could show inferior PFS and OS of MIS compared to open radical hysterectomy. The results led to a widespread debate about the best surgical approach in ECC. The present survey aimed to get first insights after publication. NOGGO and AGE conducted a nationwide digital survey among 186 Gynecological Cancer Centers. Descriptive statistics and t-tests were performed using SPSS. A majority of the centers were of high expertise and/or experience in treatment of ECC and were highly aware of the LACC trial results. Trial quality and scientific value were rated as very good/good. However, still 40% would not change the standard of care to open surgery. Centers with higher volume and participating in clinical trials were more likely to change. This survey represents insights after the surprising results of recently published trials towards the surgical approach of ECC. There still seems to be a high need of future trials and possible explanations for the unexpected worse outcomes in the MIS group.
format	article
author	Robert Armbrust Frank Chen Rolf Richter Mustafa Zela Muallem Alexander Mustea Bernd Holthaus Jalid Sehouli
author_facet	Robert Armbrust Frank Chen Rolf Richter Mustafa Zela Muallem Alexander Mustea Bernd Holthaus Jalid Sehouli
author_sort	Robert Armbrust
title	Results of a German wide survey towards current surgical approach in early stage cervical cancer NOGGO MONITOR 11
title_short	Results of a German wide survey towards current surgical approach in early stage cervical cancer NOGGO MONITOR 11
title_full	Results of a German wide survey towards current surgical approach in early stage cervical cancer NOGGO MONITOR 11
title_fullStr	Results of a German wide survey towards current surgical approach in early stage cervical cancer NOGGO MONITOR 11
title_full_unstemmed	Results of a German wide survey towards current surgical approach in early stage cervical cancer NOGGO MONITOR 11
title_sort	results of a german wide survey towards current surgical approach in early stage cervical cancer noggo monitor 11
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8f0caa5d7d8347cf8d2da1eaf6c6811d
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Results of a German wide survey towards current surgical approach in early stage cervical cancer NOGGO MONITOR 11

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