Interactions between parasitic helminths and gut microbiota in wild tropical primates from intact and fragmented habitats

Abstract The mammalian gastrointestinal tract harbours a highly complex ecosystem composed of a variety of micro- (bacteria, fungi, viruses, protozoans) and macro-organisms (helminths). Although most microbiota research focuses on the variation of single gut components, the crosstalk between compone...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Claudia Barelli, Claudio Donati, Davide Albanese, Barbora Pafčo, David Modrý, Francesco Rovero, Heidi C. Hauffe
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8f0f2c481b064e6d8721d863deb44dff
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:8f0f2c481b064e6d8721d863deb44dff
record_format	dspace
spelling	oai:doaj.org-article:8f0f2c481b064e6d8721d863deb44dff2021-11-08T10:54:32ZInteractions between parasitic helminths and gut microbiota in wild tropical primates from intact and fragmented habitats10.1038/s41598-021-01145-12045-2322https://doaj.org/article/8f0f2c481b064e6d8721d863deb44dff2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-01145-1https://doaj.org/toc/2045-2322Abstract The mammalian gastrointestinal tract harbours a highly complex ecosystem composed of a variety of micro- (bacteria, fungi, viruses, protozoans) and macro-organisms (helminths). Although most microbiota research focuses on the variation of single gut components, the crosstalk between components is still poorly characterized, especially in hosts living under natural conditions. We investigated the gut micro-biodiversity (bacteria, fungi and helminths) of 158 individuals of two wild non-human primates, the Udzungwa red colobus (Procolobus gordonorum) and the yellow baboon (Papio cynocephalus). These species have contrasting diets and lifestyles, but live sympatrically in both human-impacted and pristine forests in the Udzungwa Mountains of Tanzania. Using non-invasive faecal pellets, helminths were identified using standard microscopy while bacteria and fungi were characterized by sequencing the V1–V3 variable region of the 16S rRNA gene for bacteria and the ITS1–ITS2 fragment for fungi. Our results show that both diversity and composition of bacteria and fungi are associated with variation in helminth presence. Although interactions differed by habitat type, in both primates we found that Strongyloides was negatively associated and Trichuris was positively associated with bacterial and fungal richness. To our knowledge, this is one of the few studies demonstrating an interaction between helminth and gut microbiota communities in wild non-human primates.Claudia BarelliClaudio DonatiDavide AlbaneseBarbora PafčoDavid ModrýFrancesco RoveroHeidi C. HauffeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Claudia Barelli Claudio Donati Davide Albanese Barbora Pafčo David Modrý Francesco Rovero Heidi C. Hauffe Interactions between parasitic helminths and gut microbiota in wild tropical primates from intact and fragmented habitats
description	Abstract The mammalian gastrointestinal tract harbours a highly complex ecosystem composed of a variety of micro- (bacteria, fungi, viruses, protozoans) and macro-organisms (helminths). Although most microbiota research focuses on the variation of single gut components, the crosstalk between components is still poorly characterized, especially in hosts living under natural conditions. We investigated the gut micro-biodiversity (bacteria, fungi and helminths) of 158 individuals of two wild non-human primates, the Udzungwa red colobus (Procolobus gordonorum) and the yellow baboon (Papio cynocephalus). These species have contrasting diets and lifestyles, but live sympatrically in both human-impacted and pristine forests in the Udzungwa Mountains of Tanzania. Using non-invasive faecal pellets, helminths were identified using standard microscopy while bacteria and fungi were characterized by sequencing the V1–V3 variable region of the 16S rRNA gene for bacteria and the ITS1–ITS2 fragment for fungi. Our results show that both diversity and composition of bacteria and fungi are associated with variation in helminth presence. Although interactions differed by habitat type, in both primates we found that Strongyloides was negatively associated and Trichuris was positively associated with bacterial and fungal richness. To our knowledge, this is one of the few studies demonstrating an interaction between helminth and gut microbiota communities in wild non-human primates.
format	article
author	Claudia Barelli Claudio Donati Davide Albanese Barbora Pafčo David Modrý Francesco Rovero Heidi C. Hauffe
author_facet	Claudia Barelli Claudio Donati Davide Albanese Barbora Pafčo David Modrý Francesco Rovero Heidi C. Hauffe
author_sort	Claudia Barelli
title	Interactions between parasitic helminths and gut microbiota in wild tropical primates from intact and fragmented habitats
title_short	Interactions between parasitic helminths and gut microbiota in wild tropical primates from intact and fragmented habitats
title_full	Interactions between parasitic helminths and gut microbiota in wild tropical primates from intact and fragmented habitats
title_fullStr	Interactions between parasitic helminths and gut microbiota in wild tropical primates from intact and fragmented habitats
title_full_unstemmed	Interactions between parasitic helminths and gut microbiota in wild tropical primates from intact and fragmented habitats
title_sort	interactions between parasitic helminths and gut microbiota in wild tropical primates from intact and fragmented habitats
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8f0f2c481b064e6d8721d863deb44dff
work_keys_str_mv	AT claudiabarelli interactionsbetweenparasitichelminthsandgutmicrobiotainwildtropicalprimatesfromintactandfragmentedhabitats AT claudiodonati interactionsbetweenparasitichelminthsandgutmicrobiotainwildtropicalprimatesfromintactandfragmentedhabitats AT davidealbanese interactionsbetweenparasitichelminthsandgutmicrobiotainwildtropicalprimatesfromintactandfragmentedhabitats AT barborapafco interactionsbetweenparasitichelminthsandgutmicrobiotainwildtropicalprimatesfromintactandfragmentedhabitats AT davidmodry interactionsbetweenparasitichelminthsandgutmicrobiotainwildtropicalprimatesfromintactandfragmentedhabitats AT francescorovero interactionsbetweenparasitichelminthsandgutmicrobiotainwildtropicalprimatesfromintactandfragmentedhabitats AT heidichauffe interactionsbetweenparasitichelminthsandgutmicrobiotainwildtropicalprimatesfromintactandfragmentedhabitats
_version_	1718442544881205248

Interactions between parasitic helminths and gut microbiota in wild tropical primates from intact and fragmented habitats

Ejemplares similares