Salvage of the 5-deoxyribose byproduct of radical SAM enzymes
5-Deoxyribose is formed from 5′-deoxyadenosine, a toxic byproduct of radical S-adenosylmethionine enzymes. Here, the authors identify and biochemically characterize a bacterial salvage pathway for 5-deoxyribose, consisting of three enzymes, and solve the crystal structure of the key aldolase.
Guardado en:
Autores principales: | Guillaume A. W. Beaudoin, Qiang Li, Jacob Folz, Oliver Fiehn, Justin L. Goodsell, Alexander Angerhofer, Steven D. Bruner, Andrew D. Hanson |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/8f102546de1241ed9baef7187af4175b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Oxidative Pathways of Deoxyribose and Deoxyribonate Catabolism
por: Morgan N. Price, et al.
Publicado: (2019) -
Deoxyribose and deoxysugar derivatives from photoprocessed astrophysical ice analogues and comparison to meteorites
por: Michel Nuevo, et al.
Publicado: (2018) -
Genome mining for radical SAM protein determinants reveals multiple sactibiotic-like gene clusters.
por: Kiera Murphy, et al.
Publicado: (2011) -
Clinical Outcome of Salvage Radiotherapy for Locoregional Clinical Recurrence After Radical Prostatectomy
por: Sung Uk Lee MD, et al.
Publicado: (2021) -
Clinical outcomes of salvage treatment in lymph node-positive prostate cancer patients after radical prostatectomy.
por: Dowook Kim, et al.
Publicado: (2021)