Transgenerational propagation and quantitative maintenance of paternal centromeres depends on Cid/Cenp-A presence in Drosophila sperm.

In Drosophila melanogaster, as in many animal and plant species, centromere identity is specified epigenetically. In proliferating cells, a centromere-specific histone H3 variant (CenH3), named Cid in Drosophila and Cenp-A in humans, is a crucial component of the epigenetic centromere mark. Hence, m...

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Autores principales: Nitika Raychaudhuri, Raphaelle Dubruille, Guillermo A Orsi, Homayoun C Bagheri, Benjamin Loppin, Christian F Lehner
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/8f112dc101a14551a3dddabe303d6103
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