COMPARISON OF HAEMODYNAMIC EFFECT OF EQUIVALENT DOSE OF OXYTOCIN GIVEN AS BOLUS AND IN FUSION

Objective: To compare the haemodynamic effects of equivalent dose of oxytocin given as an intravenous bolus and as infusion. Study Design: Randomized controlled trial. Place and Duration of Study: CMH Rawalpindi from Jan 2016 to Jul 2016. Material and Methods: This randomized control trial was co...

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Autores principales:	Tariq Mahmood Malik, Syed Majid Waseem, Amera Tariq
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2018
Materias:	oxytocin hemodynamics Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/8f15a19623634c348141d3e11eaa150e
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spelling	oai:doaj.org-article:8f15a19623634c348141d3e11eaa150e2021-11-17T07:25:29ZCOMPARISON OF HAEMODYNAMIC EFFECT OF EQUIVALENT DOSE OF OXYTOCIN GIVEN AS BOLUS AND IN FUSION0030-96482411-8842https://doaj.org/article/8f15a19623634c348141d3e11eaa150e2018-12-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2409/2037https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare the haemodynamic effects of equivalent dose of oxytocin given as an intravenous bolus and as infusion. Study Design: Randomized controlled trial. Place and Duration of Study: CMH Rawalpindi from Jan 2016 to Jul 2016. Material and Methods: This randomized control trial was conducted after approval of ethical committee of the hospital and a total 90 patients, American society of anesthesiologists physical status I or II, were included in this study. Patients were divided into two groups (n=45), group-A received oxytocin (5 IU) approximately over 10 seconds as an intravenous bolus and group-B received (5 IU) over 5 minutes as an infusion in infusion pump. Mean heart rate and mean blood pressure recorded at Baseline 0, 1, 5, 10 and 15 minutes. The hemodynamic data was compared between the groups. Results: The Oxytocin when administered as an intravenous infusion showed statistically significant effects on heart rate when compared with bolus group from 1 minute to 15 minute (p<0.001). Similarly, oxytocin once administered as an intravenous infusion showed statistically significant difference in mean arterial pressure (MAP) when compared with bolus group from 1 minute to 15 minute (p<0.001). Conclusion: It is concluded that oxytocin (5IU) once administered as an infusion during elective caesarean section causes less haemodynamic changes. Tariq Mahmood MalikSyed Majid WaseemAmera TariqArmy Medical College RawalpindiarticleoxytocinhemodynamicsMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 68, Iss 6, Pp 1517-1521 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	oxytocin hemodynamics Medicine R Medicine (General) R5-920
spellingShingle	oxytocin hemodynamics Medicine R Medicine (General) R5-920 Tariq Mahmood Malik Syed Majid Waseem Amera Tariq COMPARISON OF HAEMODYNAMIC EFFECT OF EQUIVALENT DOSE OF OXYTOCIN GIVEN AS BOLUS AND IN FUSION
description	Objective: To compare the haemodynamic effects of equivalent dose of oxytocin given as an intravenous bolus and as infusion. Study Design: Randomized controlled trial. Place and Duration of Study: CMH Rawalpindi from Jan 2016 to Jul 2016. Material and Methods: This randomized control trial was conducted after approval of ethical committee of the hospital and a total 90 patients, American society of anesthesiologists physical status I or II, were included in this study. Patients were divided into two groups (n=45), group-A received oxytocin (5 IU) approximately over 10 seconds as an intravenous bolus and group-B received (5 IU) over 5 minutes as an infusion in infusion pump. Mean heart rate and mean blood pressure recorded at Baseline 0, 1, 5, 10 and 15 minutes. The hemodynamic data was compared between the groups. Results: The Oxytocin when administered as an intravenous infusion showed statistically significant effects on heart rate when compared with bolus group from 1 minute to 15 minute (p<0.001). Similarly, oxytocin once administered as an intravenous infusion showed statistically significant difference in mean arterial pressure (MAP) when compared with bolus group from 1 minute to 15 minute (p<0.001). Conclusion: It is concluded that oxytocin (5IU) once administered as an infusion during elective caesarean section causes less haemodynamic changes.
format	article
author	Tariq Mahmood Malik Syed Majid Waseem Amera Tariq
author_facet	Tariq Mahmood Malik Syed Majid Waseem Amera Tariq
author_sort	Tariq Mahmood Malik
title	COMPARISON OF HAEMODYNAMIC EFFECT OF EQUIVALENT DOSE OF OXYTOCIN GIVEN AS BOLUS AND IN FUSION
title_short	COMPARISON OF HAEMODYNAMIC EFFECT OF EQUIVALENT DOSE OF OXYTOCIN GIVEN AS BOLUS AND IN FUSION
title_full	COMPARISON OF HAEMODYNAMIC EFFECT OF EQUIVALENT DOSE OF OXYTOCIN GIVEN AS BOLUS AND IN FUSION
title_fullStr	COMPARISON OF HAEMODYNAMIC EFFECT OF EQUIVALENT DOSE OF OXYTOCIN GIVEN AS BOLUS AND IN FUSION
title_full_unstemmed	COMPARISON OF HAEMODYNAMIC EFFECT OF EQUIVALENT DOSE OF OXYTOCIN GIVEN AS BOLUS AND IN FUSION
title_sort	comparison of haemodynamic effect of equivalent dose of oxytocin given as bolus and in fusion
publisher	Army Medical College Rawalpindi
publishDate	2018
url	https://doaj.org/article/8f15a19623634c348141d3e11eaa150e
work_keys_str_mv	AT tariqmahmoodmalik comparisonofhaemodynamiceffectofequivalentdoseofoxytocingivenasbolusandinfusion AT syedmajidwaseem comparisonofhaemodynamiceffectofequivalentdoseofoxytocingivenasbolusandinfusion AT ameratariq comparisonofhaemodynamiceffectofequivalentdoseofoxytocingivenasbolusandinfusion
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COMPARISON OF HAEMODYNAMIC EFFECT OF EQUIVALENT DOSE OF OXYTOCIN GIVEN AS BOLUS AND IN FUSION

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