New and emerging therapies for the treatment of rheumatoid arthritis
Michael G FeelyDivision of Rheumatology and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, NE, USAAbstract: The introduction of tumor necrosis factor (TNF) inhibitors in the late 1990s ­significantly changed the therape...
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Dove Medical Press
2010
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oai:doaj.org-article:8f1850835f254dfabf88d3d1b8990c432021-12-02T01:34:10ZNew and emerging therapies for the treatment of rheumatoid arthritis1179-156Xhttps://doaj.org/article/8f1850835f254dfabf88d3d1b8990c432010-07-01T00:00:00Zhttp://www.dovepress.com/new-and-emerging-therapies-for-the-treatment-of-rheumatoid-arthritis-a4931https://doaj.org/toc/1179-156XMichael G FeelyDivision of Rheumatology and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, NE, USAAbstract: The introduction of tumor necrosis factor (TNF) inhibitors in the late 1990s ­significantly changed the therapeutic approach for rheumatoid arthritis (RA). With the approval of subsequent TNF inhibitors as well as other biologic agents effective in the management of RA, the treatment paradigm has become increasingly complex. This review examines the current literature regarding the efficacy and toxicity of these and other new anti-rheumatic therapies and discusses effective therapeutic strategies for their use.Keywords: biologics, tumor necrosis factor inhibitors, DMARDs, infliximab, etancercept, adalimumab, golimumab, certolizumab, abatacept, rituximab, tocilizumab Michael G FeelyDove Medical PressarticleDiseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol 2010, Iss default, Pp 35-43 (2010) |
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Diseases of the musculoskeletal system RC925-935 |
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Diseases of the musculoskeletal system RC925-935 Michael G Feely New and emerging therapies for the treatment of rheumatoid arthritis |
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Michael G FeelyDivision of Rheumatology and Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, NE, USAAbstract: The introduction of tumor necrosis factor (TNF) inhibitors in the late 1990s ­significantly changed the therapeutic approach for rheumatoid arthritis (RA). With the approval of subsequent TNF inhibitors as well as other biologic agents effective in the management of RA, the treatment paradigm has become increasingly complex. This review examines the current literature regarding the efficacy and toxicity of these and other new anti-rheumatic therapies and discusses effective therapeutic strategies for their use.Keywords: biologics, tumor necrosis factor inhibitors, DMARDs, infliximab, etancercept, adalimumab, golimumab, certolizumab, abatacept, rituximab, tocilizumab |
format |
article |
author |
Michael G Feely |
author_facet |
Michael G Feely |
author_sort |
Michael G Feely |
title |
New and emerging therapies for the treatment of rheumatoid arthritis |
title_short |
New and emerging therapies for the treatment of rheumatoid arthritis |
title_full |
New and emerging therapies for the treatment of rheumatoid arthritis |
title_fullStr |
New and emerging therapies for the treatment of rheumatoid arthritis |
title_full_unstemmed |
New and emerging therapies for the treatment of rheumatoid arthritis |
title_sort |
new and emerging therapies for the treatment of rheumatoid arthritis |
publisher |
Dove Medical Press |
publishDate |
2010 |
url |
https://doaj.org/article/8f1850835f254dfabf88d3d1b8990c43 |
work_keys_str_mv |
AT michaelgfeely newandemergingtherapiesforthetreatmentofrheumatoidarthritis |
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1718403027385188352 |