Lateral Pelvic Lymph Node Dissection for low locally advanced rectal cancer: a review

Lateral pelvic lymph node dissection for advanced low rectal cancer has generated much discussion in the literature in last few years. Whilst it is still being debated as to whether it constitutes a locoregional disease amenable to surgery, or whether it is a distant metastases requiring neoadjuvant...

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Autores principales:	JU YONG CHEONG, Peter Lee, Yoon Suk Lee, Nariman Ahmadi
Formato:	article
Lenguaje:	EN
Publicado:	Shiraz University of Medical Sciences 2020
Materias:	lateral pelvic lymph node low rectal cancer neoadjuvant therapy Medicine R
Acceso en línea:	https://doaj.org/article/8f1a7133cf27443c8c918d7332c65647
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spelling	oai:doaj.org-article:8f1a7133cf27443c8c918d7332c656472021-11-14T08:12:11ZLateral Pelvic Lymph Node Dissection for low locally advanced rectal cancer: a review2783-243010.30476/acrr.2020.46703https://doaj.org/article/8f1a7133cf27443c8c918d7332c656472020-06-01T00:00:00Zhttps://colorectalresearch.sums.ac.ir/article_46703_a9310a12b18a661b9c07e9f190b0751e.pdfhttps://doaj.org/toc/2783-2430Lateral pelvic lymph node dissection for advanced low rectal cancer has generated much discussion in the literature in last few years. Whilst it is still being debated as to whether it constitutes a locoregional disease amenable to surgery, or whether it is a distant metastases requiring neoadjuvant therapy, what is clear is that patients with enlarged lateral pelvic lymph nodes have higher rate of recurrence. In this review, we have analysed the current evidence and recommendations for lateral pelvic lymph node dissection. If advanced low rectal cancer (stage II, stage III) below peritoneal reflection, the decision to perform LPLND depends on (1) size of LPLN on MRI (>5mm) prior to neoadjuvant chemoradiotherapy and (2) non-responsive LPLN after CRT (LPLN >5mm before and after CRT). LPLN does prolong the operating time, and greater blood loss, however, is not associated with any greater morbidity. Preservation of the neurovascular structures, including the obturator nerves, hypogastric nerves, and the inferior vesical arteries must be identified and preserved. We have also described the key steps in performing lateral pelvic lymph node dissection.JU YONG CHEONGPeter LeeYoon Suk LeeNariman AhmadiShiraz University of Medical Sciencesarticlelateral pelvic lymph nodelow rectal cancerneoadjuvant therapyMedicineRENIranian Journal of Colorectal Research, Vol 8, Iss 2, Pp 65-74 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	lateral pelvic lymph node low rectal cancer neoadjuvant therapy Medicine R
spellingShingle	lateral pelvic lymph node low rectal cancer neoadjuvant therapy Medicine R JU YONG CHEONG Peter Lee Yoon Suk Lee Nariman Ahmadi Lateral Pelvic Lymph Node Dissection for low locally advanced rectal cancer: a review
description	Lateral pelvic lymph node dissection for advanced low rectal cancer has generated much discussion in the literature in last few years. Whilst it is still being debated as to whether it constitutes a locoregional disease amenable to surgery, or whether it is a distant metastases requiring neoadjuvant therapy, what is clear is that patients with enlarged lateral pelvic lymph nodes have higher rate of recurrence. In this review, we have analysed the current evidence and recommendations for lateral pelvic lymph node dissection. If advanced low rectal cancer (stage II, stage III) below peritoneal reflection, the decision to perform LPLND depends on (1) size of LPLN on MRI (>5mm) prior to neoadjuvant chemoradiotherapy and (2) non-responsive LPLN after CRT (LPLN >5mm before and after CRT). LPLN does prolong the operating time, and greater blood loss, however, is not associated with any greater morbidity. Preservation of the neurovascular structures, including the obturator nerves, hypogastric nerves, and the inferior vesical arteries must be identified and preserved. We have also described the key steps in performing lateral pelvic lymph node dissection.
format	article
author	JU YONG CHEONG Peter Lee Yoon Suk Lee Nariman Ahmadi
author_facet	JU YONG CHEONG Peter Lee Yoon Suk Lee Nariman Ahmadi
author_sort	JU YONG CHEONG
title	Lateral Pelvic Lymph Node Dissection for low locally advanced rectal cancer: a review
title_short	Lateral Pelvic Lymph Node Dissection for low locally advanced rectal cancer: a review
title_full	Lateral Pelvic Lymph Node Dissection for low locally advanced rectal cancer: a review
title_fullStr	Lateral Pelvic Lymph Node Dissection for low locally advanced rectal cancer: a review
title_full_unstemmed	Lateral Pelvic Lymph Node Dissection for low locally advanced rectal cancer: a review
title_sort	lateral pelvic lymph node dissection for low locally advanced rectal cancer: a review
publisher	Shiraz University of Medical Sciences
publishDate	2020
url	https://doaj.org/article/8f1a7133cf27443c8c918d7332c65647
work_keys_str_mv	AT juyongcheong lateralpelviclymphnodedissectionforlowlocallyadvancedrectalcancerareview AT peterlee lateralpelviclymphnodedissectionforlowlocallyadvancedrectalcancerareview AT yoonsuklee lateralpelviclymphnodedissectionforlowlocallyadvancedrectalcancerareview AT narimanahmadi lateralpelviclymphnodedissectionforlowlocallyadvancedrectalcancerareview
_version_	1718429790301585408

Lateral Pelvic Lymph Node Dissection for low locally advanced rectal cancer: a review

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