UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly

Eukaryotic ribosome biogenesis involves a large number of maturations factors which are responsible for the stepwise assembly of the ribosomal subunits. Here the authors use an array of biochemical and structural biology methods to investigate the function of the UtpA and UtpB complexes as part of t...

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Autores principales: Mirjam Hunziker, Jonas Barandun, Elisabeth Petfalski, Dongyan Tan, Clémentine Delan-Forino, Kelly R. Molloy, Kelly H. Kim, Hywel Dunn-Davies, Yi Shi, Malik Chaker-Margot, Brian T. Chait, Thomas Walz, David Tollervey, Sebastian Klinge
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Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/8f1bcb93f5c5482ca631db107b522b3f
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spelling oai:doaj.org-article:8f1bcb93f5c5482ca631db107b522b3f2021-12-02T14:38:34ZUtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly10.1038/ncomms120902041-1723https://doaj.org/article/8f1bcb93f5c5482ca631db107b522b3f2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms12090https://doaj.org/toc/2041-1723Eukaryotic ribosome biogenesis involves a large number of maturations factors which are responsible for the stepwise assembly of the ribosomal subunits. Here the authors use an array of biochemical and structural biology methods to investigate the function of the UtpA and UtpB complexes as part of the small subunit processome.Mirjam HunzikerJonas BarandunElisabeth PetfalskiDongyan TanClémentine Delan-ForinoKelly R. MolloyKelly H. KimHywel Dunn-DaviesYi ShiMalik Chaker-MargotBrian T. ChaitThomas WalzDavid TollerveySebastian KlingeNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mirjam Hunziker
Jonas Barandun
Elisabeth Petfalski
Dongyan Tan
Clémentine Delan-Forino
Kelly R. Molloy
Kelly H. Kim
Hywel Dunn-Davies
Yi Shi
Malik Chaker-Margot
Brian T. Chait
Thomas Walz
David Tollervey
Sebastian Klinge
UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly
description Eukaryotic ribosome biogenesis involves a large number of maturations factors which are responsible for the stepwise assembly of the ribosomal subunits. Here the authors use an array of biochemical and structural biology methods to investigate the function of the UtpA and UtpB complexes as part of the small subunit processome.
format article
author Mirjam Hunziker
Jonas Barandun
Elisabeth Petfalski
Dongyan Tan
Clémentine Delan-Forino
Kelly R. Molloy
Kelly H. Kim
Hywel Dunn-Davies
Yi Shi
Malik Chaker-Margot
Brian T. Chait
Thomas Walz
David Tollervey
Sebastian Klinge
author_facet Mirjam Hunziker
Jonas Barandun
Elisabeth Petfalski
Dongyan Tan
Clémentine Delan-Forino
Kelly R. Molloy
Kelly H. Kim
Hywel Dunn-Davies
Yi Shi
Malik Chaker-Margot
Brian T. Chait
Thomas Walz
David Tollervey
Sebastian Klinge
author_sort Mirjam Hunziker
title UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly
title_short UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly
title_full UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly
title_fullStr UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly
title_full_unstemmed UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly
title_sort utpa and utpb chaperone nascent pre-ribosomal rna and u3 snorna to initiate eukaryotic ribosome assembly
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/8f1bcb93f5c5482ca631db107b522b3f
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