Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention

Beatrice Vignoli et al. examine potential molecular mechanisms of long-term storage information in mice. Their results suggest that astrocytes may help convert neuronal BDNF precursor into active prodomain and mature forms to enhance post-synaptic signaling and memory, providing further insight into...

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Autores principales: Beatrice Vignoli, Gabriele Sansevero, Manju Sasi, Roberto Rimondini, Robert Blum, Valerio Bonaldo, Emiliano Biasini, Spartaco Santi, Nicoletta Berardi, Bai Lu, Marco Canossa
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8f200d647e2d488e9a5707b188533ab9
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spelling oai:doaj.org-article:8f200d647e2d488e9a5707b188533ab92021-12-02T18:01:38ZAstrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention10.1038/s42003-021-02678-x2399-3642https://doaj.org/article/8f200d647e2d488e9a5707b188533ab92021-10-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02678-xhttps://doaj.org/toc/2399-3642Beatrice Vignoli et al. examine potential molecular mechanisms of long-term storage information in mice. Their results suggest that astrocytes may help convert neuronal BDNF precursor into active prodomain and mature forms to enhance post-synaptic signaling and memory, providing further insight into the development of memory circuits.Beatrice VignoliGabriele SanseveroManju SasiRoberto RimondiniRobert BlumValerio BonaldoEmiliano BiasiniSpartaco SantiNicoletta BerardiBai LuMarco CanossaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Beatrice Vignoli
Gabriele Sansevero
Manju Sasi
Roberto Rimondini
Robert Blum
Valerio Bonaldo
Emiliano Biasini
Spartaco Santi
Nicoletta Berardi
Bai Lu
Marco Canossa
Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention
description Beatrice Vignoli et al. examine potential molecular mechanisms of long-term storage information in mice. Their results suggest that astrocytes may help convert neuronal BDNF precursor into active prodomain and mature forms to enhance post-synaptic signaling and memory, providing further insight into the development of memory circuits.
format article
author Beatrice Vignoli
Gabriele Sansevero
Manju Sasi
Roberto Rimondini
Robert Blum
Valerio Bonaldo
Emiliano Biasini
Spartaco Santi
Nicoletta Berardi
Bai Lu
Marco Canossa
author_facet Beatrice Vignoli
Gabriele Sansevero
Manju Sasi
Roberto Rimondini
Robert Blum
Valerio Bonaldo
Emiliano Biasini
Spartaco Santi
Nicoletta Berardi
Bai Lu
Marco Canossa
author_sort Beatrice Vignoli
title Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention
title_short Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention
title_full Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention
title_fullStr Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention
title_full_unstemmed Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention
title_sort astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/8f200d647e2d488e9a5707b188533ab9
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