High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing

Functional characterization of disease-causing variants at risk loci in cancer is challenging. Here, in prostate cancer the authors report a pipeline for high-throughput single-nucleotide polymorphisms sequencing (SNPs-seq) for large scale screening of functional SNPs at disease risk loci.

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Autores principales:	Peng Zhang, Ji-Han Xia, Jing Zhu, Ping Gao, Yi-Jun Tian, Meijun Du, Yong-Chen Guo, Sufyan Suleman, Qin Zhang, Manish Kohli, Lori S. Tillmans, Stephen N. Thibodeau, Amy J. French, James R. Cerhan, Li-Dong Wang, Gong-Hong Wei, Liang Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8f27bd2ddde14365ab316f8ff586c4c6
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spelling	oai:doaj.org-article:8f27bd2ddde14365ab316f8ff586c4c62021-12-02T14:40:09ZHigh-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing10.1038/s41467-018-04451-x2041-1723https://doaj.org/article/8f27bd2ddde14365ab316f8ff586c4c62018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04451-xhttps://doaj.org/toc/2041-1723Functional characterization of disease-causing variants at risk loci in cancer is challenging. Here, in prostate cancer the authors report a pipeline for high-throughput single-nucleotide polymorphisms sequencing (SNPs-seq) for large scale screening of functional SNPs at disease risk loci.Peng ZhangJi-Han XiaJing ZhuPing GaoYi-Jun TianMeijun DuYong-Chen GuoSufyan SulemanQin ZhangManish KohliLori S. TillmansStephen N. ThibodeauAmy J. FrenchJames R. CerhanLi-Dong WangGong-Hong WeiLiang WangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Peng Zhang Ji-Han Xia Jing Zhu Ping Gao Yi-Jun Tian Meijun Du Yong-Chen Guo Sufyan Suleman Qin Zhang Manish Kohli Lori S. Tillmans Stephen N. Thibodeau Amy J. French James R. Cerhan Li-Dong Wang Gong-Hong Wei Liang Wang High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing
description	Functional characterization of disease-causing variants at risk loci in cancer is challenging. Here, in prostate cancer the authors report a pipeline for high-throughput single-nucleotide polymorphisms sequencing (SNPs-seq) for large scale screening of functional SNPs at disease risk loci.
format	article
author	Peng Zhang Ji-Han Xia Jing Zhu Ping Gao Yi-Jun Tian Meijun Du Yong-Chen Guo Sufyan Suleman Qin Zhang Manish Kohli Lori S. Tillmans Stephen N. Thibodeau Amy J. French James R. Cerhan Li-Dong Wang Gong-Hong Wei Liang Wang
author_facet	Peng Zhang Ji-Han Xia Jing Zhu Ping Gao Yi-Jun Tian Meijun Du Yong-Chen Guo Sufyan Suleman Qin Zhang Manish Kohli Lori S. Tillmans Stephen N. Thibodeau Amy J. French James R. Cerhan Li-Dong Wang Gong-Hong Wei Liang Wang
author_sort	Peng Zhang
title	High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing
title_short	High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing
title_full	High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing
title_fullStr	High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing
title_full_unstemmed	High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing
title_sort	high-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/8f27bd2ddde14365ab316f8ff586c4c6
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High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing

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