Disruption of the Opal Stop Codon Attenuates Chikungunya Virus-Induced Arthritis and Pathology

Disruption of the Opal Stop Codon Attenuates Chikungunya Virus-Induced Arthritis and Pathology

ABSTRACT Chikungunya virus (CHIKV) is a mosquito-borne alphavirus responsible for several significant outbreaks of debilitating acute and chronic arthritis and arthralgia over the past decade. These include a recent outbreak in the Caribbean islands and the Americas that caused more than 1 million c...

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Bibliographic Details
Main Authors: Jennifer E. Jones, Kristin M. Long, Alan C. Whitmore, Wes Sanders, Lance R. Thurlow, Julia A. Brown, Clayton R. Morrison, Heather Vincent, Kayla M. Peck, Christian Browning, Nathaniel Moorman, Jean K. Lim, Mark T. Heise
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
alphavirus
chikungunya
opal stop codon
viral pathogenesis
Microbiology
QR1-502
Online Access:https://doaj.org/article/8f27fe69f5174573bc32b852d1bbb70e
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