Phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women.

Data concerning the effects of phthalate exposure on preterm delivery and fetal growth are limited in humans. In this paper, we assessed the relationship between 15 phthalate levels in cord blood and preterm delivery and fetal growth parameters in 207 Chinese women going into labor. Exposure to phth...

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Autores principales:	Yujing Huang, Junnan Li, Jose M Garcia, Hui Lin, Yanzhou Wang, Ping Yan, Lingqiao Wang, Yao Tan, Jiaohua Luo, Zhiqun Qiu, Ji-an Chen, Weiqun Shu
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8f2cfa213bbc4dbea6aac46ba2112eb4
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spelling	oai:doaj.org-article:8f2cfa213bbc4dbea6aac46ba2112eb42021-11-18T08:34:03ZPhthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women.1932-620310.1371/journal.pone.0087430https://doaj.org/article/8f2cfa213bbc4dbea6aac46ba2112eb42014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24503621/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Data concerning the effects of phthalate exposure on preterm delivery and fetal growth are limited in humans. In this paper, we assessed the relationship between 15 phthalate levels in cord blood and preterm delivery and fetal growth parameters in 207 Chinese women going into labor. Exposure to phthalates except DCHP was associated with gestational age reduction and preterm delivery (p<0.05). There were associations between phthalates and fetal growth parameters, many of which disappeared when analyses were adjusted for gestational age, especially in male infants (Only DEEP was associated with birth weight; DEP, DNHP, BBP, DNP with abdominal circumference; DEP, DBP, DCHP, DEHP with femur length in female infants. And DPP, DBEP was associated with birth length in male infants. p<0.05). This study indicates that prenatal exposure to phthalates is associated with younger gestational age and preterm delivery. Also, phthalate exposure may adversely affect fetal growth parameters via gestational age reduction and preterm delivery with a significant gender effect.Yujing HuangJunnan LiJose M GarciaHui LinYanzhou WangPing YanLingqiao WangYao TanJiaohua LuoZhiqun QiuJi-an ChenWeiqun ShuPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 2, p e87430 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yujing Huang Junnan Li Jose M Garcia Hui Lin Yanzhou Wang Ping Yan Lingqiao Wang Yao Tan Jiaohua Luo Zhiqun Qiu Ji-an Chen Weiqun Shu Phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women.
description	Data concerning the effects of phthalate exposure on preterm delivery and fetal growth are limited in humans. In this paper, we assessed the relationship between 15 phthalate levels in cord blood and preterm delivery and fetal growth parameters in 207 Chinese women going into labor. Exposure to phthalates except DCHP was associated with gestational age reduction and preterm delivery (p<0.05). There were associations between phthalates and fetal growth parameters, many of which disappeared when analyses were adjusted for gestational age, especially in male infants (Only DEEP was associated with birth weight; DEP, DNHP, BBP, DNP with abdominal circumference; DEP, DBP, DCHP, DEHP with femur length in female infants. And DPP, DBEP was associated with birth length in male infants. p<0.05). This study indicates that prenatal exposure to phthalates is associated with younger gestational age and preterm delivery. Also, phthalate exposure may adversely affect fetal growth parameters via gestational age reduction and preterm delivery with a significant gender effect.
format	article
author	Yujing Huang Junnan Li Jose M Garcia Hui Lin Yanzhou Wang Ping Yan Lingqiao Wang Yao Tan Jiaohua Luo Zhiqun Qiu Ji-an Chen Weiqun Shu
author_facet	Yujing Huang Junnan Li Jose M Garcia Hui Lin Yanzhou Wang Ping Yan Lingqiao Wang Yao Tan Jiaohua Luo Zhiqun Qiu Ji-an Chen Weiqun Shu
author_sort	Yujing Huang
title	Phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women.
title_short	Phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women.
title_full	Phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women.
title_fullStr	Phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women.
title_full_unstemmed	Phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women.
title_sort	phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in chinese women.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/8f2cfa213bbc4dbea6aac46ba2112eb4
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Phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women.

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