The oncogenic role of microRNA-130a/301a/454 in human colorectal cancer via targeting Smad4 expression.

Transforming growth factor (TGF)-β/Smad signaling plays an important role in colon cancer development, progression and metastasis. In this study we demonstrated that the microRNA-130a/301a/454 family is up-regulated in colon cancer tissues compared to paired adjacent normal mucosa, which share the s...

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Autores principales: Lin Liu, Jing Nie, Lin Chen, Guanglong Dong, Xiaohui Du, Xin Wu, Yun Tang, Weidong Han
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/8f35e1305468435aa1fcd60c90cc108c
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