Induction of Neutralizing Responses against Autologous Virus in Maternal HIV Vaccine Trials
ABSTRACT A maternal vaccine capable of boosting neutralizing antibody (NAb) responses directed against circulating viruses in HIV-infected pregnant women could effectively decrease mother-to-child transmission of HIV. However, it is not known if an HIV envelope (Env) vaccine administered to infected...
Guardado en:
Autores principales: | Eliza D. Hompe, Jesse F. Mangold, Amit Kumar, Joshua A. Eudailey, Erin McGuire, Barton F. Haynes, M. Anthony Moody, Peter F. Wright, Genevieve G. Fouda, Elena E. Giorgi, Feng Gao, Sallie R. Permar |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/8f3973ffb24a434595bd4de143e970da |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation
por: Christina Guzzo, et al.
Publicado: (2018) -
Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants
por: David R. Martinez, et al.
Publicado: (2020) -
A Bispecific Antibody That Simultaneously Recognizes the V2- and V3-Glycan Epitopes of the HIV-1 Envelope Glycoprotein Is Broader and More Potent than Its Parental Antibodies
por: Meredith E. Davis-Gardner, et al.
Publicado: (2020) -
Differences in the Binding Affinity of an HIV-1 V2 Apex-Specific Antibody for the SIV<sub>smm/mac</sub> Envelope Glycoprotein Uncouple Antibody-Dependent Cellular Cytotoxicity from Neutralization
por: Benjamin von Bredow, et al.
Publicado: (2019) -
Pseudotyping of HIV-1 with Human T-Lymphotropic Virus 1 (HTLV-1) Envelope Glycoprotein during HIV-1–HTLV-1 Coinfection Facilitates Direct HIV-1 Infection of Female Genital Epithelial Cells: Implications for Sexual Transmission of HIV-1
por: Yuyang Tang, et al.
Publicado: (2018)