The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease

Alzheimer’s disease, a neurodegenerative disease, is one of the most common causes of dementia if elderly people worldwide. Alzheimer’s disease leads to the alienation of individuals and their exclusion from social and professional life. It is characterized mainly by the degradation of memory and di...

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Autores principales: Anna Nowak, Klaudyna Kojder, Joanna Zielonka-Brzezicka, Jacek Wróbel, Mateusz Bosiacki, Marta Fabiańska, Mariola Wróbel, Joanna Sołek-Pastuszka, Adam Klimowicz
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Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/8f40958322a24feda238eb1d1f4fc7c6
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spelling oai:doaj.org-article:8f40958322a24feda238eb1d1f4fc7c62021-11-04T05:02:57ZThe Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease1663-981210.3389/fphar.2021.775034https://doaj.org/article/8f40958322a24feda238eb1d1f4fc7c62021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fphar.2021.775034/fullhttps://doaj.org/toc/1663-9812Alzheimer’s disease, a neurodegenerative disease, is one of the most common causes of dementia if elderly people worldwide. Alzheimer’s disease leads to the alienation of individuals and their exclusion from social and professional life. It is characterized mainly by the degradation of memory and disorientation, which occurs as a result of the loss of neuronal structure and function in different brain areas. In recent years, more and more attention has been paid to use in the treatment of natural bioactive compounds that will be effective in neurodegenerative diseases, including Alzheimer’s disease. G. biloba L. and its most frequently used standardized extract (EGb 761), have been used for many years in supportive therapy and in the prevention of cognitive disorders. The paper presents an overview of reports on the pathogenesis of Alzheimer’s disease, as well as a summary of the properties of G. biloba extract and its effects on the possible pathogenesis of the disease. By exploring more about the pathogenesis of the disease and the benefits of G. biloba extract for patients with Alzheimer’s disease, it will be possible to create an individualized therapeutic protocol to optimize the treatment.Anna NowakKlaudyna KojderJoanna Zielonka-BrzezickaJacek WróbelMateusz BosiackiMarta FabiańskaMariola WróbelJoanna Sołek-PastuszkaAdam KlimowiczFrontiers Media S.A.articleGinkgo biloba L.Alzheheimer’s diseaseneurodegenarative diseaseEGb 761 extractdementiaTherapeutics. PharmacologyRM1-950ENFrontiers in Pharmacology, Vol 12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Ginkgo biloba L.
Alzheheimer’s disease
neurodegenarative disease
EGb 761 extract
dementia
Therapeutics. Pharmacology
RM1-950
spellingShingle Ginkgo biloba L.
Alzheheimer’s disease
neurodegenarative disease
EGb 761 extract
dementia
Therapeutics. Pharmacology
RM1-950
Anna Nowak
Klaudyna Kojder
Joanna Zielonka-Brzezicka
Jacek Wróbel
Mateusz Bosiacki
Marta Fabiańska
Mariola Wróbel
Joanna Sołek-Pastuszka
Adam Klimowicz
The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
description Alzheimer’s disease, a neurodegenerative disease, is one of the most common causes of dementia if elderly people worldwide. Alzheimer’s disease leads to the alienation of individuals and their exclusion from social and professional life. It is characterized mainly by the degradation of memory and disorientation, which occurs as a result of the loss of neuronal structure and function in different brain areas. In recent years, more and more attention has been paid to use in the treatment of natural bioactive compounds that will be effective in neurodegenerative diseases, including Alzheimer’s disease. G. biloba L. and its most frequently used standardized extract (EGb 761), have been used for many years in supportive therapy and in the prevention of cognitive disorders. The paper presents an overview of reports on the pathogenesis of Alzheimer’s disease, as well as a summary of the properties of G. biloba extract and its effects on the possible pathogenesis of the disease. By exploring more about the pathogenesis of the disease and the benefits of G. biloba extract for patients with Alzheimer’s disease, it will be possible to create an individualized therapeutic protocol to optimize the treatment.
format article
author Anna Nowak
Klaudyna Kojder
Joanna Zielonka-Brzezicka
Jacek Wróbel
Mateusz Bosiacki
Marta Fabiańska
Mariola Wróbel
Joanna Sołek-Pastuszka
Adam Klimowicz
author_facet Anna Nowak
Klaudyna Kojder
Joanna Zielonka-Brzezicka
Jacek Wróbel
Mateusz Bosiacki
Marta Fabiańska
Mariola Wróbel
Joanna Sołek-Pastuszka
Adam Klimowicz
author_sort Anna Nowak
title The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
title_short The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
title_full The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
title_fullStr The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
title_full_unstemmed The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
title_sort use of ginkgo biloba l. as a neuroprotective agent in the alzheimer’s disease
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/8f40958322a24feda238eb1d1f4fc7c6
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