MCC950, the NLRP3 Inhibitor, Protects against Cartilage Degradation in a Mouse Model of Osteoarthritis

Osteoarthritis (OA), characterized by chronic systemic low-level inflammation and cartilage degeneration, is a type of arthritis closely associated with aging. Inflammation and aging play a pivotal role in the occurrence and progression of OA. NLRP3 inflammasome is involved in many inflammatory and...

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Autores principales: Bowei Ni, Wenbin Pei, Yunkun Qu, Rui Zhang, Xiangyu Chu, Yingguang Wang, Xiaojian Huang, Hongbo You
Formato: article
Lenguaje:EN
Publicado: Hindawi Limited 2021
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Acceso en línea:https://doaj.org/article/8f481312f0494438b1b4d62ccdb2d4f4
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