Validation of the Nottingham Hip Fracture Score (NHFS) in Patients with Hip Fracture: A Prospective Cohort Study in the Netherlands

Veronique AJIM van Rijckevorsel,1 Gert R Roukema,1 Taco MAL Klem,2 Tjallingius M Kuijper,3 Louis de Jong2 On behalf of Dutch Hip Fracture Registry Collaboration1Surgery Department, Maasstad Hospital, DZ Rotterdam 3079, Netherlands; 2Surgery Department, Franciscus Hospital, PM Rotterdam 3045, Netherl...

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Autores principales:	van Rijckevorsel VAJIM, Roukema GR, Klem TMAL, Kuijper TM, de Jong L
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	30 day mortality hip fractures nhfs validation prediction tool Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/8f49c0d4dce3495da3921d19e0196a60
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spelling	oai:doaj.org-article:8f49c0d4dce3495da3921d19e0196a602021-12-02T15:11:05ZValidation of the Nottingham Hip Fracture Score (NHFS) in Patients with Hip Fracture: A Prospective Cohort Study in the Netherlands1178-1998https://doaj.org/article/8f49c0d4dce3495da3921d19e0196a602021-08-01T00:00:00Zhttps://www.dovepress.com/validation-of-the-nottingham-hip-fracture-score-nhfs-in-patients-with--peer-reviewed-fulltext-article-CIAhttps://doaj.org/toc/1178-1998Veronique AJIM van Rijckevorsel,1 Gert R Roukema,1 Taco MAL Klem,2 Tjallingius M Kuijper,3 Louis de Jong2 On behalf of Dutch Hip Fracture Registry Collaboration1Surgery Department, Maasstad Hospital, DZ Rotterdam 3079, Netherlands; 2Surgery Department, Franciscus Hospital, PM Rotterdam 3045, Netherlands; 3Science Board, Maasstad Hospital, DZ Rotterdam 3079, NetherlandsCorrespondence: Veronique AJIM van Rijckevorsel Email veroniquevanrijckevorsel@gmail.comIntroduction: The Nottingham Hip Fracture Score (NHFS) was developed to predict 30-day mortality for patients with hip fracture. This study aimed to validate the NHFS in a cohort with sufficient statistical power.Methods: Data were extracted from a prospective hip-fracture database (FAMMI). Patients were included between January 1, 2018 and January 11, 2021. All consecutively admitted patients ≥ 18 years of age with a hip fracture (ie, femoral neck fracture, intertrochanteric fracture, and subtrochanteric fracture) were included. Mann–Whitney’s U values were calculated to find potential miscalibration of the NHFS formula. Discrimination evaluation was performed using the concordance statistic as an equivalent to area under the receiver-operating curve.Results: In total, 2,458 patients were included. Mean age was 80± 12 years, and 66% were women (n=1,631). Median NHFS was 5 (4– 6) and overall 30-day mortality 7.9% (n=195). Overall goodness of fit was tested with Pearson’s ?2 (11.8, df 10; P=0.297). No statistically significant signs of miscalibration were found (Mann–Whitney U, P=0.08). Discrimination was tested with area under the receiver- operating curve, which was 72.1% (95% CI 68.7%– 75.4%). However, observed 30-day mortality in our population of hip-fracture patients was slightly higher than the NHFS prediction.Conclusion: The NHFS seemed to predict 30-day mortality with reasonable accuracy for patients with a hip fracture in a population within the Netherlands.Keywords: 30-day mortality, hip fractures, NHFS, validation, prediction toolvan Rijckevorsel VAJIMRoukema GRKlem TMALKuijper TMde Jong LDove Medical Pressarticle30 day mortalityhip fracturesnhfsvalidationprediction toolGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 16, Pp 1555-1562 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	30 day mortality hip fractures nhfs validation prediction tool Geriatrics RC952-954.6
spellingShingle	30 day mortality hip fractures nhfs validation prediction tool Geriatrics RC952-954.6 van Rijckevorsel VAJIM Roukema GR Klem TMAL Kuijper TM de Jong L Validation of the Nottingham Hip Fracture Score (NHFS) in Patients with Hip Fracture: A Prospective Cohort Study in the Netherlands
description	Veronique AJIM van Rijckevorsel,1 Gert R Roukema,1 Taco MAL Klem,2 Tjallingius M Kuijper,3 Louis de Jong2 On behalf of Dutch Hip Fracture Registry Collaboration1Surgery Department, Maasstad Hospital, DZ Rotterdam 3079, Netherlands; 2Surgery Department, Franciscus Hospital, PM Rotterdam 3045, Netherlands; 3Science Board, Maasstad Hospital, DZ Rotterdam 3079, NetherlandsCorrespondence: Veronique AJIM van Rijckevorsel Email veroniquevanrijckevorsel@gmail.comIntroduction: The Nottingham Hip Fracture Score (NHFS) was developed to predict 30-day mortality for patients with hip fracture. This study aimed to validate the NHFS in a cohort with sufficient statistical power.Methods: Data were extracted from a prospective hip-fracture database (FAMMI). Patients were included between January 1, 2018 and January 11, 2021. All consecutively admitted patients ≥ 18 years of age with a hip fracture (ie, femoral neck fracture, intertrochanteric fracture, and subtrochanteric fracture) were included. Mann–Whitney’s U values were calculated to find potential miscalibration of the NHFS formula. Discrimination evaluation was performed using the concordance statistic as an equivalent to area under the receiver-operating curve.Results: In total, 2,458 patients were included. Mean age was 80± 12 years, and 66% were women (n=1,631). Median NHFS was 5 (4– 6) and overall 30-day mortality 7.9% (n=195). Overall goodness of fit was tested with Pearson’s ?2 (11.8, df 10; P=0.297). No statistically significant signs of miscalibration were found (Mann–Whitney U, P=0.08). Discrimination was tested with area under the receiver- operating curve, which was 72.1% (95% CI 68.7%– 75.4%). However, observed 30-day mortality in our population of hip-fracture patients was slightly higher than the NHFS prediction.Conclusion: The NHFS seemed to predict 30-day mortality with reasonable accuracy for patients with a hip fracture in a population within the Netherlands.Keywords: 30-day mortality, hip fractures, NHFS, validation, prediction tool
format	article
author	van Rijckevorsel VAJIM Roukema GR Klem TMAL Kuijper TM de Jong L
author_facet	van Rijckevorsel VAJIM Roukema GR Klem TMAL Kuijper TM de Jong L
author_sort	van Rijckevorsel VAJIM
title	Validation of the Nottingham Hip Fracture Score (NHFS) in Patients with Hip Fracture: A Prospective Cohort Study in the Netherlands
title_short	Validation of the Nottingham Hip Fracture Score (NHFS) in Patients with Hip Fracture: A Prospective Cohort Study in the Netherlands
title_full	Validation of the Nottingham Hip Fracture Score (NHFS) in Patients with Hip Fracture: A Prospective Cohort Study in the Netherlands
title_fullStr	Validation of the Nottingham Hip Fracture Score (NHFS) in Patients with Hip Fracture: A Prospective Cohort Study in the Netherlands
title_full_unstemmed	Validation of the Nottingham Hip Fracture Score (NHFS) in Patients with Hip Fracture: A Prospective Cohort Study in the Netherlands
title_sort	validation of the nottingham hip fracture score (nhfs) in patients with hip fracture: a prospective cohort study in the netherlands
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/8f49c0d4dce3495da3921d19e0196a60
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Validation of the Nottingham Hip Fracture Score (NHFS) in Patients with Hip Fracture: A Prospective Cohort Study in the Netherlands

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