Integrating systemic and molecular levels to infer key drivers sustaining metabolic adaptations.

Metabolic adaptations to complex perturbations, like the response to pharmacological treatments in multifactorial diseases such as cancer, can be described through measurements of part of the fluxes and concentrations at the systemic level and individual transporter and enzyme activities at the mole...

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Bibliographic Details
Main Authors: Pedro de Atauri, Míriam Tarrado-Castellarnau, Josep Tarragó-Celada, Carles Foguet, Effrosyni Karakitsou, Josep Joan Centelles, Marta Cascante
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
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Online Access:https://doaj.org/article/8f4e2159d42e41bf8158d242fb172797
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