Contribution of protein Gar1 to the RNA-guided and RNA-independent rRNA:Ψ-synthase activities of the archaeal Cbf5 protein

Contribution of protein Gar1 to the RNA-guided and RNA-independent rRNA:Ψ-synthase activities of the archaeal Cbf5 protein

Abstract Archaeal RNA:pseudouridine-synthase (PUS) Cbf5 in complex with proteins L7Ae, Nop10 and Gar1, and guide box H/ACA sRNAs forms ribonucleoprotein (RNP) catalysts that insure the conversion of uridines into pseudouridines (Ψs) in ribosomal RNAs (rRNAs). Nonetheless, in the absence of guide RNA...

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Autores principales: Ryosuke Fujikane, Isabelle Behm-Ansmant, Anne-Sophie Tillault, Christine Loegler, Valérie Igel-Bourguignon, Evelyne Marguet, Patrick Forterre, Christiane Branlant, Yuri Motorin, Bruno Charpentier
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Kodakarensis
Protein L7Ae
Protein Nopp140
Abyssal
Pseudouridylation
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/8f4e286c4b614fb4bbbba9971d936c88
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https://doaj.org/article/8f4e286c4b614fb4bbbba9971d936c88

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