Adverse clinical outcomes in people at clinical high-risk for psychosis related to altered interactions between hippocampal activity and glutamatergic function

Abstract Preclinical rodent models suggest that psychosis involves alterations in the activity and glutamatergic function in the hippocampus, driving dopamine activity through projections to the striatum. The extent to which this model applies to the onset of psychosis in clinical subjects is unclea...

Full description

Saved in:
Bibliographic Details
Main Authors: Paul Allen, Emily J. Hird, Natasza Orlov, Gemma Modinos, Matthijs Bossong, Mathilde Antoniades, Carly Sampson, Matilda Azis, Oliver Howes, James Stone, Jesus Perez, Matthew Broome, Antony A. Grace, Philip McGuire
Format: article
Language:EN
Published: Nature Publishing Group 2021
Subjects:
Online Access:https://doaj.org/article/8f67679a12be4d6f8abeb8495cd43e50
Tags: Add Tag
No Tags, Be the first to tag this record!