Redox Sensitive Cysteine Residues as Crucial Regulators of Wild-Type and Mutant p53 Isoforms
The wild-type protein p53 plays a key role in preventing the formation of neoplasms by controlling cell growth. However, in more than a half of all cancers, the <i>TP53</i> gene has missense mutations that appear during tumorigenesis. In most cases, the mutated gene encodes a full-length...
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Autores principales: | Elena Butturini, Giovanna Butera, Raffaella Pacchiana, Alessandra Carcereri de Prati, Sofia Mariotto, Massimo Donadelli |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Acceso en línea: | https://doaj.org/article/8f6cb1b86bad4870b96b979da2adcf92 |
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