Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia

The fusion of two genes during the pathogenesis of cancer can create oncogenes. In this study, the authors screen pediatric B-cell precursor acute lymphoblastic leukaemia samples for the presence of fusion genes and describe fusion genes that define new molecular subtypes of the disease

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Autores principales:	Henrik Lilljebjörn, Rasmus Henningsson, Axel Hyrenius-Wittsten, Linda Olsson, Christina Orsmark-Pietras, Sofia von Palffy, Maria Askmyr, Marianne Rissler, Martin Schrappe, Gunnar Cario, Anders Castor, Cornelis J. H. Pronk, Mikael Behrendtz, Felix Mitelman, Bertil Johansson, Kajsa Paulsson, Anna K. Andersson, Magnus Fontes, Thoas Fioretos
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8f786cff4cc2473789fedd4b0c20a6c4
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spelling	oai:doaj.org-article:8f786cff4cc2473789fedd4b0c20a6c42021-12-02T15:35:44ZIdentification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia10.1038/ncomms117902041-1723https://doaj.org/article/8f786cff4cc2473789fedd4b0c20a6c42016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11790https://doaj.org/toc/2041-1723The fusion of two genes during the pathogenesis of cancer can create oncogenes. In this study, the authors screen pediatric B-cell precursor acute lymphoblastic leukaemia samples for the presence of fusion genes and describe fusion genes that define new molecular subtypes of the diseaseHenrik LilljebjörnRasmus HenningssonAxel Hyrenius-WittstenLinda OlssonChristina Orsmark-PietrasSofia von PalffyMaria AskmyrMarianne RisslerMartin SchrappeGunnar CarioAnders CastorCornelis J. H. PronkMikael BehrendtzFelix MitelmanBertil JohanssonKajsa PaulssonAnna K. AnderssonMagnus FontesThoas FioretosNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Henrik Lilljebjörn Rasmus Henningsson Axel Hyrenius-Wittsten Linda Olsson Christina Orsmark-Pietras Sofia von Palffy Maria Askmyr Marianne Rissler Martin Schrappe Gunnar Cario Anders Castor Cornelis J. H. Pronk Mikael Behrendtz Felix Mitelman Bertil Johansson Kajsa Paulsson Anna K. Andersson Magnus Fontes Thoas Fioretos Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
description	The fusion of two genes during the pathogenesis of cancer can create oncogenes. In this study, the authors screen pediatric B-cell precursor acute lymphoblastic leukaemia samples for the presence of fusion genes and describe fusion genes that define new molecular subtypes of the disease
format	article
author	Henrik Lilljebjörn Rasmus Henningsson Axel Hyrenius-Wittsten Linda Olsson Christina Orsmark-Pietras Sofia von Palffy Maria Askmyr Marianne Rissler Martin Schrappe Gunnar Cario Anders Castor Cornelis J. H. Pronk Mikael Behrendtz Felix Mitelman Bertil Johansson Kajsa Paulsson Anna K. Andersson Magnus Fontes Thoas Fioretos
author_facet	Henrik Lilljebjörn Rasmus Henningsson Axel Hyrenius-Wittsten Linda Olsson Christina Orsmark-Pietras Sofia von Palffy Maria Askmyr Marianne Rissler Martin Schrappe Gunnar Cario Anders Castor Cornelis J. H. Pronk Mikael Behrendtz Felix Mitelman Bertil Johansson Kajsa Paulsson Anna K. Andersson Magnus Fontes Thoas Fioretos
author_sort	Henrik Lilljebjörn
title	Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
title_short	Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
title_full	Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
title_fullStr	Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
title_full_unstemmed	Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
title_sort	identification of etv6-runx1-like and dux4-rearranged subtypes in paediatric b-cell precursor acute lymphoblastic leukaemia
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/8f786cff4cc2473789fedd4b0c20a6c4
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Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia

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