Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc

In myelinated fibres conduction and adhesion proteins aggregate at discrete foci, but it is unclear if this organization is present in other excitable cells. Using nanoscale visualization and in silico techniques, the authors show that adhesion/excitability nodes exist at the intercalated discs of a...

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Autores principales: Alejandra Leo-Macias, Esperanza Agullo-Pascual, Jose L. Sanchez-Alonso, Sarah Keegan, Xianming Lin, Tatiana Arcos, Feng-Xia-Liang, Yuri E. Korchev, Julia Gorelik, David Fenyö, Eli Rothenberg, Mario Delmar
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/8f789436985642779f392dca037fd860
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spelling oai:doaj.org-article:8f789436985642779f392dca037fd8602021-12-02T17:33:09ZNanoscale visualization of functional adhesion/excitability nodes at the intercalated disc10.1038/ncomms103422041-1723https://doaj.org/article/8f789436985642779f392dca037fd8602016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10342https://doaj.org/toc/2041-1723In myelinated fibres conduction and adhesion proteins aggregate at discrete foci, but it is unclear if this organization is present in other excitable cells. Using nanoscale visualization and in silico techniques, the authors show that adhesion/excitability nodes exist at the intercalated discs of adult cardiac muscle.Alejandra Leo-MaciasEsperanza Agullo-PascualJose L. Sanchez-AlonsoSarah KeeganXianming LinTatiana ArcosFeng-Xia-LiangYuri E. KorchevJulia GorelikDavid FenyöEli RothenbergMario DelmarNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alejandra Leo-Macias
Esperanza Agullo-Pascual
Jose L. Sanchez-Alonso
Sarah Keegan
Xianming Lin
Tatiana Arcos
Feng-Xia-Liang
Yuri E. Korchev
Julia Gorelik
David Fenyö
Eli Rothenberg
Mario Delmar
Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc
description In myelinated fibres conduction and adhesion proteins aggregate at discrete foci, but it is unclear if this organization is present in other excitable cells. Using nanoscale visualization and in silico techniques, the authors show that adhesion/excitability nodes exist at the intercalated discs of adult cardiac muscle.
format article
author Alejandra Leo-Macias
Esperanza Agullo-Pascual
Jose L. Sanchez-Alonso
Sarah Keegan
Xianming Lin
Tatiana Arcos
Feng-Xia-Liang
Yuri E. Korchev
Julia Gorelik
David Fenyö
Eli Rothenberg
Mario Delmar
author_facet Alejandra Leo-Macias
Esperanza Agullo-Pascual
Jose L. Sanchez-Alonso
Sarah Keegan
Xianming Lin
Tatiana Arcos
Feng-Xia-Liang
Yuri E. Korchev
Julia Gorelik
David Fenyö
Eli Rothenberg
Mario Delmar
author_sort Alejandra Leo-Macias
title Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc
title_short Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc
title_full Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc
title_fullStr Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc
title_full_unstemmed Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc
title_sort nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/8f789436985642779f392dca037fd860
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