A hypomorphic cystathionine ß-synthase gene contributes to cavefish eye loss by disrupting optic vasculature

The teleost Astyanax mexicanus has sighted morphs living in surface rivers and various blind morphs living in caves. Here, the authors suggest that loss of eyes in cave morphs is linked to mutations in the cystathionine ß-synthase a (cbsa) gene, which cause eye degeneration by disrupting function of...

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Autores principales:	Li Ma, Aniket V. Gore, Daniel Castranova, Janet Shi, Mandy Ng, Kelly A. Tomins, Corine M. van der Weele, Brant M. Weinstein, William R. Jeffery
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8f7dfeb6d2e649afae92c3bc5f98d827
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spelling	oai:doaj.org-article:8f7dfeb6d2e649afae92c3bc5f98d8272021-12-02T18:24:49ZA hypomorphic cystathionine ß-synthase gene contributes to cavefish eye loss by disrupting optic vasculature10.1038/s41467-020-16497-x2041-1723https://doaj.org/article/8f7dfeb6d2e649afae92c3bc5f98d8272020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16497-xhttps://doaj.org/toc/2041-1723The teleost Astyanax mexicanus has sighted morphs living in surface rivers and various blind morphs living in caves. Here, the authors suggest that loss of eyes in cave morphs is linked to mutations in the cystathionine ß-synthase a (cbsa) gene, which cause eye degeneration by disrupting function of the optic circulatory system.Li MaAniket V. GoreDaniel CastranovaJanet ShiMandy NgKelly A. TominsCorine M. van der WeeleBrant M. WeinsteinWilliam R. JefferyNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Li Ma Aniket V. Gore Daniel Castranova Janet Shi Mandy Ng Kelly A. Tomins Corine M. van der Weele Brant M. Weinstein William R. Jeffery A hypomorphic cystathionine ß-synthase gene contributes to cavefish eye loss by disrupting optic vasculature
description	The teleost Astyanax mexicanus has sighted morphs living in surface rivers and various blind morphs living in caves. Here, the authors suggest that loss of eyes in cave morphs is linked to mutations in the cystathionine ß-synthase a (cbsa) gene, which cause eye degeneration by disrupting function of the optic circulatory system.
format	article
author	Li Ma Aniket V. Gore Daniel Castranova Janet Shi Mandy Ng Kelly A. Tomins Corine M. van der Weele Brant M. Weinstein William R. Jeffery
author_facet	Li Ma Aniket V. Gore Daniel Castranova Janet Shi Mandy Ng Kelly A. Tomins Corine M. van der Weele Brant M. Weinstein William R. Jeffery
author_sort	Li Ma
title	A hypomorphic cystathionine ß-synthase gene contributes to cavefish eye loss by disrupting optic vasculature
title_short	A hypomorphic cystathionine ß-synthase gene contributes to cavefish eye loss by disrupting optic vasculature
title_full	A hypomorphic cystathionine ß-synthase gene contributes to cavefish eye loss by disrupting optic vasculature
title_fullStr	A hypomorphic cystathionine ß-synthase gene contributes to cavefish eye loss by disrupting optic vasculature
title_full_unstemmed	A hypomorphic cystathionine ß-synthase gene contributes to cavefish eye loss by disrupting optic vasculature
title_sort	hypomorphic cystathionine ß-synthase gene contributes to cavefish eye loss by disrupting optic vasculature
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/8f7dfeb6d2e649afae92c3bc5f98d827
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A hypomorphic cystathionine ß-synthase gene contributes to cavefish eye loss by disrupting optic vasculature

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