Telomerase reverse transcriptase synergizes with calorie restriction to increase health span and extend mouse longevity.
Caloric restriction (CR), a reduction of food intake while avoiding malnutrition, can delay the onset of cancer and age-related diseases in several species, including mice. In addition, depending of the genetic background, CR can also increase or decrease mouse longevity. This has highlighted the im...
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Main Authors: | Elsa Vera, Bruno Bernardes de Jesus, Miguel Foronda, Juana M Flores, Maria A Blasco |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/8f7fba8dd6f641bfa6c085b5d64d3f8d |
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