RA3 is a reference-guided approach for epigenetic characterization of single cells

Methods for profiling differences between individual cells are constantly expanding. Here, the authors present a computational framework for the analysis of chromatin accessibility data at the single-cell level that takes into account previous knowledge and data-specific characteristics.

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Autores principales: Shengquan Chen, Guanao Yan, Wenyu Zhang, Jinzhao Li, Rui Jiang, Zhixiang Lin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8f88f00d4c944301a88b5d18925223bb
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spelling oai:doaj.org-article:8f88f00d4c944301a88b5d18925223bb2021-12-02T14:25:17ZRA3 is a reference-guided approach for epigenetic characterization of single cells10.1038/s41467-021-22495-42041-1723https://doaj.org/article/8f88f00d4c944301a88b5d18925223bb2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22495-4https://doaj.org/toc/2041-1723Methods for profiling differences between individual cells are constantly expanding. Here, the authors present a computational framework for the analysis of chromatin accessibility data at the single-cell level that takes into account previous knowledge and data-specific characteristics.Shengquan ChenGuanao YanWenyu ZhangJinzhao LiRui JiangZhixiang LinNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shengquan Chen
Guanao Yan
Wenyu Zhang
Jinzhao Li
Rui Jiang
Zhixiang Lin
RA3 is a reference-guided approach for epigenetic characterization of single cells
description Methods for profiling differences between individual cells are constantly expanding. Here, the authors present a computational framework for the analysis of chromatin accessibility data at the single-cell level that takes into account previous knowledge and data-specific characteristics.
format article
author Shengquan Chen
Guanao Yan
Wenyu Zhang
Jinzhao Li
Rui Jiang
Zhixiang Lin
author_facet Shengquan Chen
Guanao Yan
Wenyu Zhang
Jinzhao Li
Rui Jiang
Zhixiang Lin
author_sort Shengquan Chen
title RA3 is a reference-guided approach for epigenetic characterization of single cells
title_short RA3 is a reference-guided approach for epigenetic characterization of single cells
title_full RA3 is a reference-guided approach for epigenetic characterization of single cells
title_fullStr RA3 is a reference-guided approach for epigenetic characterization of single cells
title_full_unstemmed RA3 is a reference-guided approach for epigenetic characterization of single cells
title_sort ra3 is a reference-guided approach for epigenetic characterization of single cells
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/8f88f00d4c944301a88b5d18925223bb
work_keys_str_mv AT shengquanchen ra3isareferenceguidedapproachforepigeneticcharacterizationofsinglecells
AT guanaoyan ra3isareferenceguidedapproachforepigeneticcharacterizationofsinglecells
AT wenyuzhang ra3isareferenceguidedapproachforepigeneticcharacterizationofsinglecells
AT jinzhaoli ra3isareferenceguidedapproachforepigeneticcharacterizationofsinglecells
AT ruijiang ra3isareferenceguidedapproachforepigeneticcharacterizationofsinglecells
AT zhixianglin ra3isareferenceguidedapproachforepigeneticcharacterizationofsinglecells
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