RNA sequencing reveals changes in the microRNAome of transdifferentiating hepatic stellate cells that are conserved between human and rat

Abstract MicroRNAs are small (~ 22nt long) noncoding RNAs (ncRNAs) that regulate gene expression at the post-transcriptional level. Over 2000 microRNAs have been described in humans and many are implicated in human pathologies including tissue fibrosis. Hepatic stellate cells (HSC) are the major cel...

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Autores principales: Laura Sabater, Luigi Locatelli, Fiona Oakley, Timothy Hardy, Jeremy French, Stuart M. Robinson, Gourab Sen, D. A. Mann, Jelena Mann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8f906b3b042a46b4911aff0dbd9c06a0
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