Assessing the impact of copy number variants on miRNA genes in autism by Monte Carlo simulation.

Assessing the impact of copy number variants on miRNA genes in autism by Monte Carlo simulation.

Autism Spectrum Disorders (ASDs) are childhood neurodevelopmental disorders with complex genetic origins. Previous studies have investigated the role of de novo Copy Number Variants (CNVs) and microRNAs as important but distinct etiological factors in ASD. We developed a novel computational procedur...

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Autores principales: Maurizio Marrale, Nadia Ninfa Albanese, Francesco Calì, Valentino Romano
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/8f9a3730d269460fa62200284971f6d6
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