Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy

Objective: The primary aim was to compare the psychometric properties among the Patient Health Questionnaire (PHQ-9) (both including and excluding somatic symptom items), the depression subscale of the Hospital Anxiety and Depression Scale (HADS-D), and the Center for Epidemiologic Studies Depressi...

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Autores principales: Kantanut Yutrirak, Woraphat Ratta-apha, Pittaya Dankulchai, Panate Pukrittayakamee
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Lenguaje:EN
Publicado: Mahidol University 2021
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spelling oai:doaj.org-article:8f9cfe44d7fc464890fcbf48b9b8ddc72021-12-01T10:07:39ZPsychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy10.33192/Smj.2021.1032228-8082https://doaj.org/article/8f9cfe44d7fc464890fcbf48b9b8ddc72021-12-01T00:00:00Zhttps://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/254587https://doaj.org/toc/2228-8082 Objective: The primary aim was to compare the psychometric properties among the Patient Health Questionnaire (PHQ-9) (both including and excluding somatic symptom items), the depression subscale of the Hospital Anxiety and Depression Scale (HADS-D), and the Center for Epidemiologic Studies Depression Scale (CES-D) in detecting depression in cancer patients receiving radiotherapy. The secondary aim was to investigate the prevalence of depression in this group of patients. Materials and Methods: Overall, 198 participants with cancer diagnosis from a radiology clinic took part in the study. They completed PHQ-9, HADS-D, and CES-D questionnaires and were interviewed in line with the Mini-International Neuropsychiatric Interview (M.I.N.I.) to confirm the diagnosis. The PHQ-9 was analyzed for three scoring methods: sum-score, inclusive (including all items), and exclusive (excluding 4 somatic symptom items) methods. The psychometric properties of each questionnaire were analyzed. The prevalence of depression measured by the M.I.N.I. was evaluated. Results: The sum-score method of the PHQ-9 had an equal sensitivity (100%) to the HADS-D and CES-D, and had a slightly higher specificity (91.1%) than the HADS-D (87.4%) and CES-D (90.6%). When compared results within the PHQ-9, the sum-score method had greater sensitivity than the inclusive (71.4%) and exclusive (42.9%) methods, and had a slightly lower specificity than the inclusive (96.9%) and exclusive (97.4%) methods. The prevalence of depression assessed by the M.I.N.I was 3.5%. Conclusion: The sum-score method of the PHQ-9 seemed to be the best tool to use for depression screening in cancer patients receiving radiotherapy due to its excellent sensitivity and specificity. Kantanut YutrirakWoraphat Ratta-aphaPittaya DankulchaiPanate PukrittayakameeMahidol UniversityarticlePHQ-9HADSCES-DDepressionCancerRadiotherapyMedicine (General)R5-920ENSiriraj Medical Journal, Vol 73, Iss 12 (2021)
institution DOAJ
collection DOAJ
language EN
topic PHQ-9
HADS
CES-D
Depression
Cancer
Radiotherapy
Medicine (General)
R5-920
spellingShingle PHQ-9
HADS
CES-D
Depression
Cancer
Radiotherapy
Medicine (General)
R5-920
Kantanut Yutrirak
Woraphat Ratta-apha
Pittaya Dankulchai
Panate Pukrittayakamee
Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy
description Objective: The primary aim was to compare the psychometric properties among the Patient Health Questionnaire (PHQ-9) (both including and excluding somatic symptom items), the depression subscale of the Hospital Anxiety and Depression Scale (HADS-D), and the Center for Epidemiologic Studies Depression Scale (CES-D) in detecting depression in cancer patients receiving radiotherapy. The secondary aim was to investigate the prevalence of depression in this group of patients. Materials and Methods: Overall, 198 participants with cancer diagnosis from a radiology clinic took part in the study. They completed PHQ-9, HADS-D, and CES-D questionnaires and were interviewed in line with the Mini-International Neuropsychiatric Interview (M.I.N.I.) to confirm the diagnosis. The PHQ-9 was analyzed for three scoring methods: sum-score, inclusive (including all items), and exclusive (excluding 4 somatic symptom items) methods. The psychometric properties of each questionnaire were analyzed. The prevalence of depression measured by the M.I.N.I. was evaluated. Results: The sum-score method of the PHQ-9 had an equal sensitivity (100%) to the HADS-D and CES-D, and had a slightly higher specificity (91.1%) than the HADS-D (87.4%) and CES-D (90.6%). When compared results within the PHQ-9, the sum-score method had greater sensitivity than the inclusive (71.4%) and exclusive (42.9%) methods, and had a slightly lower specificity than the inclusive (96.9%) and exclusive (97.4%) methods. The prevalence of depression assessed by the M.I.N.I was 3.5%. Conclusion: The sum-score method of the PHQ-9 seemed to be the best tool to use for depression screening in cancer patients receiving radiotherapy due to its excellent sensitivity and specificity.
format article
author Kantanut Yutrirak
Woraphat Ratta-apha
Pittaya Dankulchai
Panate Pukrittayakamee
author_facet Kantanut Yutrirak
Woraphat Ratta-apha
Pittaya Dankulchai
Panate Pukrittayakamee
author_sort Kantanut Yutrirak
title Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy
title_short Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy
title_full Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy
title_fullStr Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy
title_full_unstemmed Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy
title_sort psychometric properties of the phq-9, hads, and ces-d questionnaires and the prevalence of depression in patients with cancer receiving radiotherapy
publisher Mahidol University
publishDate 2021
url https://doaj.org/article/8f9cfe44d7fc464890fcbf48b9b8ddc7
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AT pittayadankulchai psychometricpropertiesofthephq9hadsandcesdquestionnairesandtheprevalenceofdepressioninpatientswithcancerreceivingradiotherapy
AT panatepukrittayakamee psychometricpropertiesofthephq9hadsandcesdquestionnairesandtheprevalenceofdepressioninpatientswithcancerreceivingradiotherapy
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