Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy
Objective: The primary aim was to compare the psychometric properties among the Patient Health Questionnaire (PHQ-9) (both including and excluding somatic symptom items), the depression subscale of the Hospital Anxiety and Depression Scale (HADS-D), and the Center for Epidemiologic Studies Depressi...
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Mahidol University
2021
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oai:doaj.org-article:8f9cfe44d7fc464890fcbf48b9b8ddc72021-12-01T10:07:39ZPsychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy10.33192/Smj.2021.1032228-8082https://doaj.org/article/8f9cfe44d7fc464890fcbf48b9b8ddc72021-12-01T00:00:00Zhttps://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/254587https://doaj.org/toc/2228-8082 Objective: The primary aim was to compare the psychometric properties among the Patient Health Questionnaire (PHQ-9) (both including and excluding somatic symptom items), the depression subscale of the Hospital Anxiety and Depression Scale (HADS-D), and the Center for Epidemiologic Studies Depression Scale (CES-D) in detecting depression in cancer patients receiving radiotherapy. The secondary aim was to investigate the prevalence of depression in this group of patients. Materials and Methods: Overall, 198 participants with cancer diagnosis from a radiology clinic took part in the study. They completed PHQ-9, HADS-D, and CES-D questionnaires and were interviewed in line with the Mini-International Neuropsychiatric Interview (M.I.N.I.) to confirm the diagnosis. The PHQ-9 was analyzed for three scoring methods: sum-score, inclusive (including all items), and exclusive (excluding 4 somatic symptom items) methods. The psychometric properties of each questionnaire were analyzed. The prevalence of depression measured by the M.I.N.I. was evaluated. Results: The sum-score method of the PHQ-9 had an equal sensitivity (100%) to the HADS-D and CES-D, and had a slightly higher specificity (91.1%) than the HADS-D (87.4%) and CES-D (90.6%). When compared results within the PHQ-9, the sum-score method had greater sensitivity than the inclusive (71.4%) and exclusive (42.9%) methods, and had a slightly lower specificity than the inclusive (96.9%) and exclusive (97.4%) methods. The prevalence of depression assessed by the M.I.N.I was 3.5%. Conclusion: The sum-score method of the PHQ-9 seemed to be the best tool to use for depression screening in cancer patients receiving radiotherapy due to its excellent sensitivity and specificity. Kantanut YutrirakWoraphat Ratta-aphaPittaya DankulchaiPanate PukrittayakameeMahidol UniversityarticlePHQ-9HADSCES-DDepressionCancerRadiotherapyMedicine (General)R5-920ENSiriraj Medical Journal, Vol 73, Iss 12 (2021) |
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PHQ-9 HADS CES-D Depression Cancer Radiotherapy Medicine (General) R5-920 |
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PHQ-9 HADS CES-D Depression Cancer Radiotherapy Medicine (General) R5-920 Kantanut Yutrirak Woraphat Ratta-apha Pittaya Dankulchai Panate Pukrittayakamee Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy |
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Objective: The primary aim was to compare the psychometric properties among the Patient Health Questionnaire (PHQ-9) (both including and excluding somatic symptom items), the depression subscale of the Hospital Anxiety and Depression Scale (HADS-D), and the Center for Epidemiologic Studies Depression Scale (CES-D) in detecting depression in cancer patients receiving radiotherapy. The secondary aim was to investigate the prevalence of depression in this group of patients.
Materials and Methods: Overall, 198 participants with cancer diagnosis from a radiology clinic took part in the study. They completed PHQ-9, HADS-D, and CES-D questionnaires and were interviewed in line with the Mini-International Neuropsychiatric Interview (M.I.N.I.) to confirm the diagnosis. The PHQ-9 was analyzed for three scoring methods: sum-score, inclusive (including all items), and exclusive (excluding 4 somatic symptom items) methods. The psychometric properties of each questionnaire were analyzed. The prevalence of depression measured by the M.I.N.I. was evaluated.
Results: The sum-score method of the PHQ-9 had an equal sensitivity (100%) to the HADS-D and CES-D, and had a slightly higher specificity (91.1%) than the HADS-D (87.4%) and CES-D (90.6%). When compared results within the PHQ-9, the sum-score method had greater sensitivity than the inclusive (71.4%) and exclusive (42.9%) methods, and had a slightly lower specificity than the inclusive (96.9%) and exclusive (97.4%) methods. The prevalence of depression assessed by the M.I.N.I was 3.5%.
Conclusion: The sum-score method of the PHQ-9 seemed to be the best tool to use for depression screening in cancer patients receiving radiotherapy due to its excellent sensitivity and specificity.
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format |
article |
author |
Kantanut Yutrirak Woraphat Ratta-apha Pittaya Dankulchai Panate Pukrittayakamee |
author_facet |
Kantanut Yutrirak Woraphat Ratta-apha Pittaya Dankulchai Panate Pukrittayakamee |
author_sort |
Kantanut Yutrirak |
title |
Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy |
title_short |
Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy |
title_full |
Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy |
title_fullStr |
Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy |
title_full_unstemmed |
Psychometric Properties of the PHQ-9, HADS, and CES-D Questionnaires and the Prevalence of Depression in Patients with Cancer Receiving Radiotherapy |
title_sort |
psychometric properties of the phq-9, hads, and ces-d questionnaires and the prevalence of depression in patients with cancer receiving radiotherapy |
publisher |
Mahidol University |
publishDate |
2021 |
url |
https://doaj.org/article/8f9cfe44d7fc464890fcbf48b9b8ddc7 |
work_keys_str_mv |
AT kantanutyutrirak psychometricpropertiesofthephq9hadsandcesdquestionnairesandtheprevalenceofdepressioninpatientswithcancerreceivingradiotherapy AT woraphatrattaapha psychometricpropertiesofthephq9hadsandcesdquestionnairesandtheprevalenceofdepressioninpatientswithcancerreceivingradiotherapy AT pittayadankulchai psychometricpropertiesofthephq9hadsandcesdquestionnairesandtheprevalenceofdepressioninpatientswithcancerreceivingradiotherapy AT panatepukrittayakamee psychometricpropertiesofthephq9hadsandcesdquestionnairesandtheprevalenceofdepressioninpatientswithcancerreceivingradiotherapy |
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