Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressiveness.

<h4>Background</h4>The ambiguous role of transcription factor Sp3 for tumour progression is still debated since it was described as a transcriptional repressor or activator. Here we tried to decipher the molecular mechanisms implicated in Sp3 accumulation observed in aggressive tumours.&...

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Autores principales: Khadija Essafi-Benkhadir, Sébastien Grosso, Alexandre Puissant, Guillaume Robert, Makram Essafi, Marcel Deckert, Emmanuel Chamorey, Olivier Dassonville, Gérard Milano, Patrick Auberger, Gilles Pagès
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/8f9e91c49ae54cd29cd0fa7d34e258ec
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