Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressiveness.
<h4>Background</h4>The ambiguous role of transcription factor Sp3 for tumour progression is still debated since it was described as a transcriptional repressor or activator. Here we tried to decipher the molecular mechanisms implicated in Sp3 accumulation observed in aggressive tumours.&...
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Autores principales: | Khadija Essafi-Benkhadir, Sébastien Grosso, Alexandre Puissant, Guillaume Robert, Makram Essafi, Marcel Deckert, Emmanuel Chamorey, Olivier Dassonville, Gérard Milano, Patrick Auberger, Gilles Pagès |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2009
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Materias: | |
Acceso en línea: | https://doaj.org/article/8f9e91c49ae54cd29cd0fa7d34e258ec |
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