Monitoring treatment response in psoriasis: current perspectives on the clinical utility of reflectance confocal microscopy

Marina Agozzino,1 Cecilia Noal,2 Francesco Lacarrubba,3 Marco Ardigò4 1Dermatology Unit, Second University of Naples, Naples, 2Dermatology Unit, University of Trieste, Trieste, 3Dermatology Clinic, University of Catania, Catania, 4Clinical Dermatology Department, San Gallicano Dermatologi...

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Autores principales:	Agozzino M, Noal C, Lacarrubba F, Ardigò M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Reflectance confocal microscopy psoriasis non invasive follow up psoriasis monitoring Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/8fad7dbe00a4453c872b893b7a7fc2ab
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spelling	oai:doaj.org-article:8fad7dbe00a4453c872b893b7a7fc2ab2021-12-02T05:40:16ZMonitoring treatment response in psoriasis: current perspectives on the clinical utility of reflectance confocal microscopy2230-326Xhttps://doaj.org/article/8fad7dbe00a4453c872b893b7a7fc2ab2017-02-01T00:00:00Zhttps://www.dovepress.com/monitoring-treatment-response-in-psoriasis-current-perspectives-on-the-peer-reviewed-article-PTThttps://doaj.org/toc/2230-326XMarina Agozzino,1 Cecilia Noal,2 Francesco Lacarrubba,3 Marco Ardigò4 1Dermatology Unit, Second University of Naples, Naples, 2Dermatology Unit, University of Trieste, Trieste, 3Dermatology Clinic, University of Catania, Catania, 4Clinical Dermatology Department, San Gallicano Dermatological Institute, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy Abstract: Reflectance confocal microscopy (RCM) evaluation of inflammatory skin diseases represents a relatively new technique that, during the past 5 years, has attracted increasing interest, with consequent progressive increment of publications in literature. The success of RCM is directly related to the high need for noninvasive techniques able to both reduce the number of skin biopsies and support clinical diagnosis and patient management. RCM helps to visualize microscopic descriptors of plaque psoriasis (PP) with good reproducibility between observers and a high grade of correspondence with histopathology. Several clinical tests are used for the therapeutic management of PP, but they are limited by subjective interpretation. Skin biopsy presents objective interpretation, but the procedure is invasive and not repeatable. RCM has been used not only for the evaluation of skin cancer or inflammatory skin diseases, but also for monitoring the efficacy of different treatments in PP. In this review, we present some examples of RCM applications in therapeutic psoriasis follow-up. Keywords: reflectance confocal microscopy, psoriasis noninvasive follow-up, psoriasis monitoringAgozzino MNoal CLacarrubba FArdigò MDove Medical PressarticleReflectance confocal microscopypsoriasis non invasive follow uppsoriasis monitoringDermatologyRL1-803ENPsoriasis: Targets and Therapy, Vol Volume 7, Pp 27-34 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Reflectance confocal microscopy psoriasis non invasive follow up psoriasis monitoring Dermatology RL1-803
spellingShingle	Reflectance confocal microscopy psoriasis non invasive follow up psoriasis monitoring Dermatology RL1-803 Agozzino M Noal C Lacarrubba F Ardigò M Monitoring treatment response in psoriasis: current perspectives on the clinical utility of reflectance confocal microscopy
description	Marina Agozzino,1 Cecilia Noal,2 Francesco Lacarrubba,3 Marco Ardigò4 1Dermatology Unit, Second University of Naples, Naples, 2Dermatology Unit, University of Trieste, Trieste, 3Dermatology Clinic, University of Catania, Catania, 4Clinical Dermatology Department, San Gallicano Dermatological Institute, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy Abstract: Reflectance confocal microscopy (RCM) evaluation of inflammatory skin diseases represents a relatively new technique that, during the past 5 years, has attracted increasing interest, with consequent progressive increment of publications in literature. The success of RCM is directly related to the high need for noninvasive techniques able to both reduce the number of skin biopsies and support clinical diagnosis and patient management. RCM helps to visualize microscopic descriptors of plaque psoriasis (PP) with good reproducibility between observers and a high grade of correspondence with histopathology. Several clinical tests are used for the therapeutic management of PP, but they are limited by subjective interpretation. Skin biopsy presents objective interpretation, but the procedure is invasive and not repeatable. RCM has been used not only for the evaluation of skin cancer or inflammatory skin diseases, but also for monitoring the efficacy of different treatments in PP. In this review, we present some examples of RCM applications in therapeutic psoriasis follow-up. Keywords: reflectance confocal microscopy, psoriasis noninvasive follow-up, psoriasis monitoring
format	article
author	Agozzino M Noal C Lacarrubba F Ardigò M
author_facet	Agozzino M Noal C Lacarrubba F Ardigò M
author_sort	Agozzino M
title	Monitoring treatment response in psoriasis: current perspectives on the clinical utility of reflectance confocal microscopy
title_short	Monitoring treatment response in psoriasis: current perspectives on the clinical utility of reflectance confocal microscopy
title_full	Monitoring treatment response in psoriasis: current perspectives on the clinical utility of reflectance confocal microscopy
title_fullStr	Monitoring treatment response in psoriasis: current perspectives on the clinical utility of reflectance confocal microscopy
title_full_unstemmed	Monitoring treatment response in psoriasis: current perspectives on the clinical utility of reflectance confocal microscopy
title_sort	monitoring treatment response in psoriasis: current perspectives on the clinical utility of reflectance confocal microscopy
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/8fad7dbe00a4453c872b893b7a7fc2ab
work_keys_str_mv	AT agozzinom monitoringtreatmentresponseinpsoriasiscurrentperspectivesontheclinicalutilityofreflectanceconfocalmicroscopy AT noalc monitoringtreatmentresponseinpsoriasiscurrentperspectivesontheclinicalutilityofreflectanceconfocalmicroscopy AT lacarrubbaf monitoringtreatmentresponseinpsoriasiscurrentperspectivesontheclinicalutilityofreflectanceconfocalmicroscopy AT ardigom monitoringtreatmentresponseinpsoriasiscurrentperspectivesontheclinicalutilityofreflectanceconfocalmicroscopy
_version_	1718400309700591616

Monitoring treatment response in psoriasis: current perspectives on the clinical utility of reflectance confocal microscopy

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