Treatment of peripheral exudative hemorrhagic chorioretinopathy by intravitreal injections of ranibizumab

Kei Takayama,1 Tosio Enoki,1,2 Teruo Kojima,1,2 Sho Ishikawa,1 Masaru Takeuchi,11Department of Ophthalmology, National Defense Medical College, Saitama, Japan; 2Enoki Clinic, Saitama, JapanAbstract: Peripheral exudative hemorrhagic chorioretinopathy (PEHCR) is a rare disorder that sometimes causes s...

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Autores principales:	Takayama K, Enoki T, Kojima T, Ishikawa S, Takeuchi M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/8fba179c7cf24da7ac04db006062dcef
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spelling	oai:doaj.org-article:8fba179c7cf24da7ac04db006062dcef2021-12-02T05:36:42ZTreatment of peripheral exudative hemorrhagic chorioretinopathy by intravitreal injections of ranibizumab1177-54671177-5483https://doaj.org/article/8fba179c7cf24da7ac04db006062dcef2012-06-01T00:00:00Zhttp://www.dovepress.com/treatment-of-peripheral-exudative-hemorrhagic-chorioretinopathy-by-int-a10056https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Kei Takayama,1 Tosio Enoki,1,2 Teruo Kojima,1,2 Sho Ishikawa,1 Masaru Takeuchi,11Department of Ophthalmology, National Defense Medical College, Saitama, Japan; 2Enoki Clinic, Saitama, JapanAbstract: Peripheral exudative hemorrhagic chorioretinopathy (PEHCR) is a rare disorder that sometimes causes sudden subretinal and/or vitreous hemorrhage. Choroidal neovascularization is involved in the pathogenesis, but the etiology is unknown. Treatments with photocoagulation, cryopexy, and intravitreal bevacizumab injection have been reported. However, the therapeutic effect of intravitreal injection with ranibizumab for PEHCR is unclear. A 70-year-old woman visited our department because of sudden loss of superior visual field in her left eye. She had a history of surgical removal of hematoma due to subretinal hemorrhage associated with age-related macular degeneration 5 years ago. Peripheral subretinal hemorrhage was observed in the left eye, and fluorescein and indocyanine green angiography revealed choroidal neovascularization in the subretinal hemorrhagic region. PEHCR was diagnosed. Considering her past history, intravitreal ranibizumab injection was used for treatment. After three injections in the left eye, subretinal hemorrhage and choroidal neovascularization resolved completely. No recurrence was observed during 1 year of follow-up. This case demonstrates that intravitreal injection of ranibizumab is an effective treatment for PEHCR with subretinal hemorrhage.Keywords: peripheral exudative hemorrhagic chorioretinopathy, ranibizumab, intravitreal injection, choroidal neovascularizationTakayama KEnoki TKojima TIshikawa STakeuchi MDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 865-869 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Takayama K Enoki T Kojima T Ishikawa S Takeuchi M Treatment of peripheral exudative hemorrhagic chorioretinopathy by intravitreal injections of ranibizumab
description	Kei Takayama,1 Tosio Enoki,1,2 Teruo Kojima,1,2 Sho Ishikawa,1 Masaru Takeuchi,11Department of Ophthalmology, National Defense Medical College, Saitama, Japan; 2Enoki Clinic, Saitama, JapanAbstract: Peripheral exudative hemorrhagic chorioretinopathy (PEHCR) is a rare disorder that sometimes causes sudden subretinal and/or vitreous hemorrhage. Choroidal neovascularization is involved in the pathogenesis, but the etiology is unknown. Treatments with photocoagulation, cryopexy, and intravitreal bevacizumab injection have been reported. However, the therapeutic effect of intravitreal injection with ranibizumab for PEHCR is unclear. A 70-year-old woman visited our department because of sudden loss of superior visual field in her left eye. She had a history of surgical removal of hematoma due to subretinal hemorrhage associated with age-related macular degeneration 5 years ago. Peripheral subretinal hemorrhage was observed in the left eye, and fluorescein and indocyanine green angiography revealed choroidal neovascularization in the subretinal hemorrhagic region. PEHCR was diagnosed. Considering her past history, intravitreal ranibizumab injection was used for treatment. After three injections in the left eye, subretinal hemorrhage and choroidal neovascularization resolved completely. No recurrence was observed during 1 year of follow-up. This case demonstrates that intravitreal injection of ranibizumab is an effective treatment for PEHCR with subretinal hemorrhage.Keywords: peripheral exudative hemorrhagic chorioretinopathy, ranibizumab, intravitreal injection, choroidal neovascularization
format	article
author	Takayama K Enoki T Kojima T Ishikawa S Takeuchi M
author_facet	Takayama K Enoki T Kojima T Ishikawa S Takeuchi M
author_sort	Takayama K
title	Treatment of peripheral exudative hemorrhagic chorioretinopathy by intravitreal injections of ranibizumab
title_short	Treatment of peripheral exudative hemorrhagic chorioretinopathy by intravitreal injections of ranibizumab
title_full	Treatment of peripheral exudative hemorrhagic chorioretinopathy by intravitreal injections of ranibizumab
title_fullStr	Treatment of peripheral exudative hemorrhagic chorioretinopathy by intravitreal injections of ranibizumab
title_full_unstemmed	Treatment of peripheral exudative hemorrhagic chorioretinopathy by intravitreal injections of ranibizumab
title_sort	treatment of peripheral exudative hemorrhagic chorioretinopathy by intravitreal injections of ranibizumab
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/8fba179c7cf24da7ac04db006062dcef
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Treatment of peripheral exudative hemorrhagic chorioretinopathy by intravitreal injections of ranibizumab

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